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FKBP14

  • Official Full Name

    FK506 binding protein 14, 22 kDa

  • Overview

    The protein encoded by this gene is a member of the FK506-binding protein family of peptidyl-prolyl cis-trans;isomerases. The encoded protein is found in the lumen of the endoplasmic reticulum, where it is thought to accelerate;protein folding. Defects in this gene are a cause of a type of Ehlers-Danlos syndrome (EDS). Both a protein-coding;variant and noncoding variants are transcribed from this gene.
  • Synonyms

    FKBP14; FK506 binding protein 14, 22 kDa; FK506 binding protein 14 (22 kDa); peptidyl-prolyl cis-trans isomerase FKBP14; FKBP22; FLJ20731; 22 kDa FK506 binding protein; 22 kDa FK506-binding protein; 22 kDa FKBP; FK506 binding protein 14; FK506-binding protein 14; FKB14_HUMAN; FKBP 22; FKBP-14; FKBP-22; Peptidyl prolyl cis trans isomerase; PPIase; PPIase FKBP14; Rotamase; OTTHUMP00000122625;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FKBP14-2574H Recombinant Human FK506 Binding Protein 14, 22 kDa, His-tagged E.coli His
Human FKBP14-28911TH Recombinant Human FKBP14, His-tagged E.coli His 192 amino acids
Human FKBP14-1230H Recombinant Human FKBP14 Mammalian Cell His
Human FKBP14-12908H Recombinant Human FKBP14, GST-tagged E.coli GST 21-211a.a.
Human FKBP14-570H Recombinant Human FKBP14, His tagged Human Cell N/A
Human FKBP14-1149HCL Recombinant Human FKBP14 cell lysate Human Cell N/A
Human FKBP14-2953H-B Recombinant Human FKBP14 Protein Pre-coupled Magnetic Beads HEK293
Human FKBP14-1097H Recombinant Human FKBP14 protein(Met1-Lys207), His-tagged HEK293 C-His Met1-Lys207
Human FKBP14-4185H Recombinant Human FKBP14 Protein, GST-tagged Wheat Germ GST
Human FKBP14-4792HF Recombinant Full Length Human FKBP14 Protein, GST-tagged In Vitro Cell Free System GST 211 amino acids
Human FKBP14-2229H Recombinant Human FKBP14 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human FKBP14-6197H Recombinant Human FKBP14 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FKBP14-4805H Recombinant Human FKBP14 protein, His-SUMO-tagged E.coli His-SUMO 20-211aa
Human FKBP14-2953H Recombinant Human FKBP14 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse FKBP14-5902M Recombinant Mouse FKBP14 Protein Mammalian Cell His
Mouse Fkbp14-3021M Recombinant Mouse Fkbp14 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse FKBP14-3266M Recombinant Mouse FKBP14 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse FKBP14-3266M-B Recombinant Mouse FKBP14 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque FKBP14-1717R Recombinant Rhesus monkey FKBP14 Protein, His-tagged Mammalian Cell His
Rhesus Macaque FKBP14-1539R Recombinant Rhesus Macaque FKBP14 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque FKBP14-1539R-B Recombinant Rhesus Macaque FKBP14 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish FKBP14-917Z Recombinant Zebrafish FKBP14 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

FKBP14 involved in several pathways and played different roles in them. We selected most pathways FKBP14 participated on our site, such as IRE1alpha activates chaperones, Metabolism of proteins, Unfolded Protein Response (UPR), which may be useful for your reference. Also, other proteins which involved in the same pathway with FKBP14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
IRE1alpha activates chaperonesDNAJB9;CXXC1;SERP1;WIPI1;HDGF;SEC61B;PREB;YIF1A;TPP1
Metabolism of proteinsWDR85;ARL2;CNIH;B3GNT8;TOMM70A;GAS6;FBXL5;NEU4;GPR116
Unfolded Protein Response (UPR)FKBP14;PDIA6;YIF1A;YY2;HYOU1;C19orf10;ASNA1;TPP1;DNAJB9
XBP1(S) activates chaperone genesC19orf10;HDGF;TPP1;SEC63;KDELR3;CTDSP2;KLHDC3;WIPI1;DDX11

FKBP14 has several biochemical functions, for example, FK506 binding, calcium ion binding, peptidyl-prolyl cis-trans isomerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FKBP14 itself. We selected most functions FKBP14 had, and list some proteins which have the same functions with FKBP14. You can find most of the proteins on our site.

Function Related Protein
FK506 bindingFKBP6;FKBP7;FKBP11;FKBP1AA;FKBP1A;FKBP4;FKBP8;FKBP2;TTC9C
calcium ion bindingSLC24A4;MMP14A;EFHB;PCDH1G9;EFCAB1;MGP;FBN1;CAPSL;CAPN2
peptidyl-prolyl cis-trans isomerase activityFKBP6;PPIL2;FKBP3;FKBP7;FKBP9;FKBP11;FKBP14;PPIL1;FKBP2

FKBP14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FKBP14 here. Most of them are supplied by our site. Hope this information will be useful for your research of FKBP14.

POLR2E; GSK3B; HIST2H4B

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