g3bp1
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  • Official Full Name
  • GTPase activating protein (SH3 domain) binding protein 1
  • Background
  • This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
  • Synonyms
  • G3BP1; GTPase activating protein (SH3 domain) binding protein 1; ras GTPase-activating protein-binding protein 1; G3BP; HDH VIII; Ras GTPase activating protein SH3 domain binding protein; G3BP-1; GAP binding protein; ATP-dependent DNA helicase VIII; GAP S
Cat.#:G3BP1-4609HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human G3BP1 Protein, GST-tagged
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Cat.#:G3BP1-1295HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GTPase Activating Protein (SH3 Domain) Binding Protein 1
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Cat.#:G3BP1-13076HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human G3BP1, GST-tagged
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Cat.#:G3BP1-6127MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse G3BP1 Protein
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Cat.#:G3BP1-1781RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey G3BP1 Protein, His-tagged
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Cat.#:G3BP1-1302CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken G3BP1
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Cat.#:G3BP1-10322ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish G3BP1
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Cat.#:G3BP1-6085HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human G3BP1 293 Cell Lysate
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Protein Function

G3BP1 has several biochemical functions, for example, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by G3BP1 itself. We selected most functions G3BP1 had, and list some proteins which have the same functions with G3BP1. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PRKCHA; NMNAT1; OAS1; FER; KIFC1; RUNX2; KIF4; DDR1; HELZ2; EPHA2A
Function ATP-dependent DNA helicase activity
Related Protein BLM; DDX11; ERCC3; DHX9; FBXO18; WRN; DDX3X; CHD4; CHD1; RECQL
Function ATP-dependent RNA helicase activity
Related Protein DHX37; DDX42; DHX16; DQX1; DDX17; DDX10; DDX39; DDX53; SUPV3L1; DDX51
Function DNA binding
Related Protein HIST1H101; ZBTB44; DEAF1; THAP5; FOXN4; HIST1H3C; KRBA2; ZNF565; ISX; MAFA
Function endonuclease activity
Related Protein EAR14; RNASE2; RNASE7; EME2; ENDOU2; RNASEL4; RAG1; EAR3; EXOG; DIS3
Function mRNA binding
Related Protein RPS2; CSTF3; RBM8A; LUC7L; RC3H2; TYMS; SNRPC; FMR1; QKI; RBFOX2
Function poly(A) RNA binding
Related Protein MSI2; SAMD4A; RPL23; EFTUD2; GOT2; PRPF6; KIAA0020; SF3B14; AKAP17A; CPEB4
Function protein binding
Related Protein CORO6; MYO1C; QARS; NCDN; EPAS1; CCDC103; NRXN1; MAP3K8; RXFP4; MYO1E

Interacting Protein

G3BP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with G3BP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of G3BP1.
ATXN2L; RPTOR; CSK; LCK; ATXN2; EIF4G1