|Official Full Name||GTPase activating protein (SH3 domain) binding protein 1|
|Background||This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.|
|Synonyms||G3BP1; GTPase activating protein (SH3 domain) binding protein 1; ras GTPase-activating protein-binding protein 1; G3BP; HDH VIII; Ras GTPase activating protein SH3 domain binding protein; G3BP-1; GAP binding protein; ATP-dependent DNA helicase VIII; GAP S|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
G3BP1 involved in several pathways and played different roles in them. We selected most pathways G3BP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with G3BP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
G3BP1 has several biochemical functions, for example, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by G3BP1 itself. We selected most functions G3BP1 had, and list some proteins which have the same functions with G3BP1. You can find most of the proteins on our site.
|ATP binding||PLK1; MYH9A; PIM3; ADK; PRKCQ; MERTK; DNA2; HLTF; MYO9B; PFKFB2|
|ATP-dependent DNA helicase activity||CHD2; FBXO18; DDX11; RECQL; BRIP1; CHD4; XRCC5; RTEL1; XRCC6; CHD1|
|ATP-dependent RNA helicase activity||DHX57; DDX39A; DDX47; DDX3; DDX39AA; DDX31; DHX37; DHX29; DDX27; EIF4A1B|
|DNA binding||NUCB2; SPRTN; BRIP1; NR0B1; H2AFY; ZNF180; ZFP39; NFE2L2; POLL; APEX1|
|endonuclease activity||ANG; CENPT; EAR4; G3BP1; RNASE3; APEX1; DNASE2A; EAR14; DIS3; EXOG|
|mRNA binding||CPSF6; HSP26; LUC7L; IGF2BP1; CCDC55; EIF4A3; ZFP36L1; EIF4A1; SNRPC; MRPS7|
|poly(A) RNA binding||FLYWCH2; STRAP; BCLAF1; RNPS1; PAN3; POP7; DHX9; RBM47; MRPL28; AGO1|
|protein binding||MYBL2; PSEN1; RPA3; LOX; C1QTNF9B-AS1; ABLIM1; EXO1; KCNJ9; C6; SPTSSB|
G3BP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with G3BP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of G3BP1.
ATXN2L; RPTOR; CSK; LCK; ATXN2; EIF4G1