G3BP1 Protein, GTPase activating protein (SH3 domain) binding protein 1

G3BP1

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G3BP1

Official Full Name GTPase activating protein (SH3 domain) binding protein 1
Background This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Synonyms G3BP1; GTPase activating protein (SH3 domain) binding protein 1; ras GTPase-activating protein-binding protein 1; G3BP; HDH VIII; Ras GTPase activating protein SH3 domain binding protein; G3BP-1; GAP binding protein; ATP-dependent DNA helicase VIII; GAP S
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human G3BP1-1295H Recombinant Human GTPase Activating Protein (SH3 Domain) Binding Protein 1 Human N/A
    Human G3BP1-13076H Recombinant Human G3BP1, GST-tagged E.coli GST
    Human G3BP1-4609H Recombinant Human G3BP1 Protein, GST-tagged Wheat Germ GST
    Human G3BP1-6085HCL Recombinant Human G3BP1 293 Cell Lysate HEK293 N/A
    Mouse G3BP1-6127M Recombinant Mouse G3BP1 Protein Mammalian Cell His
    Rhesus Macaque G3BP1-1781R Recombinant Rhesus monkey G3BP1 Protein, His-tagged Mammalian Cell His
    Chicken G3BP1-1302C Recombinant Chicken G3BP1 Mammalian Cell His
    Zebrafish G3BP1-10322Z Recombinant Zebrafish G3BP1 Mammalian Cell His

    G3BP1 involved in several pathways and played different roles in them. We selected most pathways G3BP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with G3BP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    G3BP1 has several biochemical functions, for example, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by G3BP1 itself. We selected most functions G3BP1 had, and list some proteins which have the same functions with G3BP1. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding PLK1; MYH9A; PIM3; ADK; PRKCQ; MERTK; DNA2; HLTF; MYO9B; PFKFB2
    ATP-dependent DNA helicase activity CHD2; FBXO18; DDX11; RECQL; BRIP1; CHD4; XRCC5; RTEL1; XRCC6; CHD1
    ATP-dependent RNA helicase activity DHX57; DDX39A; DDX47; DDX3; DDX39AA; DDX31; DHX37; DHX29; DDX27; EIF4A1B
    DNA binding NUCB2; SPRTN; BRIP1; NR0B1; H2AFY; ZNF180; ZFP39; NFE2L2; POLL; APEX1
    endonuclease activity ANG; CENPT; EAR4; G3BP1; RNASE3; APEX1; DNASE2A; EAR14; DIS3; EXOG
    mRNA binding CPSF6; HSP26; LUC7L; IGF2BP1; CCDC55; EIF4A3; ZFP36L1; EIF4A1; SNRPC; MRPS7
    poly(A) RNA binding FLYWCH2; STRAP; BCLAF1; RNPS1; PAN3; POP7; DHX9; RBM47; MRPL28; AGO1
    protein binding MYBL2; PSEN1; RPA3; LOX; C1QTNF9B-AS1; ABLIM1; EXO1; KCNJ9; C6; SPTSSB

    G3BP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with G3BP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of G3BP1.

    ATXN2L; RPTOR; CSK; LCK; ATXN2; EIF4G1

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