Recombinant Human G3BP1 Protein, GST-tagged

• Cat.No.: G3BP1-4609H
• Product Overview: Human G3BP full-length ORF ( NP_005745.1, 1 a.a. - 466 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 78.6 kDa
• AA Sequence: MVMEKPSPLLVGREFVRQYYTLLNQ APDMLHRFYGKNSSYVHGGLDSNGK PADAVYGQKEIHRKVMSQNFTNCHT KIRHVDAHATLNDGVVVQVMGLLSN NNQALRRFMQTFVLAPEGSVANKFY VHNDIFRYQDEVFGGFVTEPQEESE EEVEEPEERQQTPEVVPDDSGTFYD QAVVSNDMEEHLEEPVAEPEPDPEP EPEQEPVSEIQEEKPEPVLEETAPE DAQKSSSPAPADIAQTVQEDLRTFS WASVTSKNLPPSGAVPVTGIPPHVV KVPASQPRPESKPESQIPPQRPQRD QRVREQRINIPPQRGPRPIREAGEQ GDIEPRRMVRHPDSHQLFIGNLPHE VDKSELKDFFQSYGNVVELRINSGG KLPNFGFVVFDDSEPVQKVLSNRPI MFRGEVRLNVEEKKTRAAREGDRRD NRLRGPGGPRGGLGGGMRGPPRGGM VQKPGFGVGRGLAPRQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: G3BP1 GTPase activating protein (SH3 domain) binding protein 1 [ Homo sapiens ]
• Official Symbol: G3BP1
• Synonyms: G3BP1; GTPase activating protein (SH3 domain) binding protein 1; ras GTPase-activating protein-binding protein 1; G3BP; HDH VIII; Ras GTPase activating protein SH3 domain binding protein; G3BP-1; GAP binding protein; ATP-dependent DNA helicase VIII; GAP SH3 domain-binding protein 1; RasGAP-associated endoribonuclease G3BP; Ras-GTPase-activating protein SH3-domain-binding protein; HDH-VIII; MGC111040
• Gene ID: 10146
• mRNA Refseq: NM_005754
• Protein Refseq: NP_005745
• MIM: 608431
• UniProt ID: Q13283