Recombinant Full Length Human G3BP1 Protein, C-Flag-tagged

• Cat.No.: G3BP1-766HFL
• Product Overview: Recombinant Full Length Human G3BP1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 52 kDa
• AA Sequence: MVMEKPSPLLVGREFVRQYYTLLNQ APDMLHRFYGKNSSYVHGGLDSNGK PADAVYGQKEIHRKVMSQNF TNCHTKIRHVDAHATLNDGVVVQVM GLLSNNNQALRRFMQTFVLAPEGSV ANKFYVHNDIFRYQDEVFGG FVTEPQEESEEEVEEPEERQQTPEV VPDDSGTFYDQAVVSNDMEEHLEEP VAEPEPDPEPEPEQEPVSEI QEEKPEPVLEETAPEDAQKSSSPAP ADIAQTVQEDLRTFSWASVTSKNLP PSGAVPVTGIPPHVVKVPAS QPRPESKPESQIPPQRPQRDQRVRE QRINIPPQRGPRPIREAGEQGDIEP RRMVRHPDSHQLFIGNLPHE VDKSELKDFFQSYGNVVELRINSGG KLPNFGFVVFDDSEPVQKVLSNRPI MFRGEVRLNVEEKKTRAARE
  GDRRDNRLRGPGGPRGGLGGGMRGP PRGGMVQKPGFGVGRGLAPRQTRTR PLEQKLISEEDLAANDILDYKDDDD KV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: G3BP1 G3BP stress granule assembly factor 1 [ Homo sapiens (human) ]
• Official Symbol: G3BP1
• Synonyms: G3BP; HDH-VIII
• Gene ID: 10146
• mRNA Refseq: NM_005754.3
• Protein Refseq: NP_005745.1
• MIM: 608431
• UniProt ID: Q13283