gabra5
Share
  • Official Full Name
  • gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
  • Synonyms
  • GABRA5; gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5; gamma-aminobutyric acid receptor subunit alpha-5; GABAA receptor alpha5 subunit; GABA(A) receptor subunit alpha-5; ligand-gated ion channel subunit; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 5; A230018I05Rik
Cat.#:GABRA5-4641HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GABRA5 Protein, GST-tagged
+Inquiry
Cat.#:GABRA5-13095HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GABRA5, GST-tagged
+Inquiry
Cat.#:GABRA5-2446RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GABRA5 Protein
+Inquiry
Cat.#:GABRA5-6063HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human GABRA5 293 Cell Lysate
+Inquiry

Involved Pathway

Gabra5 involved in several pathways and played different roles in them. We selected most pathways Gabra5 participated on our site, such as Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with Gabra5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Neuroactive ligand-receptor interaction
DRD2B; GHSRA; GLRA2; ADRA2DA; GRIK1; MC5R; TAAR14E; CHRNA2; AGTR1B; KISS1RB
Retrograde endocannabinoid signaling
GABRA4; GABRA2; GRM5; GABRA3; GNB2; FAAH; GABRB3; GNG11; GABRA1; GRIA4
GABAergic synapse
GABRB2; GABRA6; GABRB1; GNG4; GAD1; GABRQ; GABRA2; PRKACA; SLC38A5; PRKCG
Morphine addiction
GABRB2; PDE8B; PDE7A; PDE3B; GABRB3; GNG3; PDE3A; ADRBK2; GNG12; PDE1B
Nicotine addiction
GABRR1; GABRG3; GRIN1; GABRA3; GABRR3; GABRQ; GABRB1; GRIN3B; GRIA4; GABRG1

Protein Function

Gabra5 has several biochemical functions, for example, GABA receptor binding, contributes_to GABA-A receptor activity, contributes_to benzodiazepine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Gabra5 itself. We selected most functions Gabra5 had, and list some proteins which have the same functions with Gabra5. You can find most of the proteins on our site.
Function
Related Protein
Function GABA receptor binding
Related Protein PLCL2; GABARAPL1; AKAP5; GABRG1; GABARAP; GABRB1; GABARAPA; GABARAPL2; PLCL1; MAF1
Function contributes_to GABA-A receptor activity
Related Protein GABRG2; GABRZ; GABRR2A; GABRA4; GABRG1; GABRA6A; GABRQ; GABRA6; GABRR3A; GABRP
Function contributes_to benzodiazepine receptor activity
Related Protein GABRG3; GABRA1; GABRA6A; GABRE; GABRG1; GABRA5
Function chloride channel activity
Related Protein SLC26A7; SLC26A3.2; GABRR1; TTYH2; GABRA3; CLIC5B; CLCA1; TTYH3B; SLC26A5; CLIC1
Function inhibitory extracellular ligand-gated ion channel activity
Related Protein GABRA3; GABRG2; GABRA4; GABRA6A; GABRG1; GABRA2; GABRA1; GABRA5; GABRG3; GABRA6
Function receptor activity
Related Protein NOTCH1A; CD93; KLRC4-KLRK1; TNFRSF17; GRIA3A; LRP1; VMN1R49; KLRB1F; MED17; ANTXR2B
Function transporter activity
Related Protein ABCB8; SYPA; STEAP2; SLC23A1; IGF2R; AP1G1; AP3D1; CRABP1B; ABCC6; SLC13A5

Gabra5 Related Articles

Ochoa-Lubinoff, CA; Berry-Kravis, EA; et al. Safety and Tolerability of RG1662, a Selective Negative Allosteric Modulator of the GABAA+/-5 Receptor (GABRA5), in Young Adults With Down Syndrome. JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS 36:S18-S18(2015).
Khan, WA; Rogan, PK; et al. Localized, non-random differences in chromatin accessibility between homologous metaphase chromosomes. MOLECULAR CYTOGENETICS 7:-(2014).