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Official Full Name group-specific component (vitamin D binding protein)
Background The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
Synonyms GC; group-specific component (vitamin D binding protein); DBP; GRD3; VDBG; VDBP; DBP/GC; HEL-S-51; vitamin D-binding protein; VDB; gc-globulin; vitamin D-binding alpha-globulin; epididymis secretory protein Li 51;
    • Species :
    • Chicken
    • HSV-1
    • HSV-2
    • Human
    • Mouse
    • Rat
    • RVFV
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human Plasma
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    RVFV GC-707R Recombinant RVFV GC Protein (Cys691-Ser1139) (Strain MP12), His-tagged Insect Cell His
    Human GC-1222H Recombinant Human GC Protein, His-tagged E.coli His
    Human GC-1320H Recombinant Human GC Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human GC-1824H Recombinant Human GC protein, His-tagged E.coli His
    Human GC-1825H Recombinant Human GC protein, His & T7-tagged E.coli His/T7
    Human GC-1826H Recombinant Human GC protein, His & GST-tagged E.coli His/GST
    Human GC-198H Native Human GC-Globulin Human Plasma N/A
    Human GC-200H Recombinant Human GC Protein, His-tagged HEK293 His
    Human GC-224H Recombinant Human GC Mammalian Cell His
    Human GC-25H Human Vitamin D Binding Protein Reference Standard N/A
    Human GC-29857TH Native Human GC N/A
    Human GC-4785H Recombinant Human GC Protein, GST-tagged Wheat Germ GST
    Human GC-524H Native Human GC protein Human Plasma N/A
    Human GC-5995HCL Recombinant Human GC 293 Cell Lysate HEK293 N/A
    Mouse Gc-1827M Recombinant Mouse Gc protein, His-tagged E.coli His
    Mouse Gc-1828M Recombinant Mouse Gc protein, His & GST-tagged E.coli His/GST
    Mouse GC-6254M Recombinant Mouse GC Protein Mammalian Cell His
    Rat Gc-1829R Recombinant Rat Gc protein, His-tagged E.coli His
    Rat Gc-93R Rat Vitamin D Binding Protein (VDB) Reference Standard N/A
    Chicken GC-6445C Recombinant Chicken GC Mammalian Cell His
    Zebrafish GC-689Z Recombinant Zebrafish GC Mammalian Cell His
    HSV-1 gC-1699H Recombinant HSV-1 gC Protein HEK293 N/A
    HSV-2 gC-333V Recombinant HSV-2 gC (Ectodomain) Protein, His-tagged HEK293 His

    GC involved in several pathways and played different roles in them. We selected most pathways GC participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with GC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism COQ6; CYP11B1; ACOT9; SPRB; PAOX; LOC100686744; SLC25A11; ACY3.2; ATP5L; RHAG
    Metabolism of lipids and lipoproteins PEMT; CYP8B2; COQ6; GGTLC1; GDF1; SIN3B; GC; CHKB; FABP12; ABHD3
    Metabolism of steroid hormones and vitamin D CYP27B1; HSD17B11; AKR1B15; CYP24A1; GC; CYP2R1; STARD5; PPP1R2
    Vitamin D (calciferol) metabolism GC
    Vitamin D synthesis GC

    GC has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by GC itself. We selected most functions GC had, and list some proteins which have the same functions with GC. You can find most of the proteins on our site.

    Function Related Protein
    actin binding DIXDC1; SYN1; WASLA; S100A4; TMOD3; PTK2; TNNI1; ALDOA; ACTN2B; MYO1H
    calcidiol binding GC
    vitamin D binding CALB1; VDRA; GC; S100G
    vitamin transporter activity GC; STRA6

    GC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GC here. Most of them are supplied by our site. Hope this information will be useful for your research of GC.

    ACTA1; p29991-pro_0000037941; CCND3; GRB2; SERF2; RIF1; CDC73; PIK3R3; d-mannose; PPP2R2A

    Sun, RY; Zhuang, HS; et al. An indirect competitive biotin-streptavidin enzyme-linked immunosorbent assay for the determination of dimethyl phthalate (DMP) in milk and milk products. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES 50:275-284(2015).
    Wernike, K; Brocchi, E; et al. A novel panel of monoclonal antibodies against Schmallenberg virus nucleoprotein and glycoprotein Gc allows specific orthobunyavirus detection and reveals antigenic differences. VETERINARY RESEARCH 46:-(2015).

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