gc
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  • Official Full Name
  • group-specific component (vitamin D binding protein)
  • Background
  • The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
  • Synonyms
  • GC; group-specific component (vitamin D binding protein); DBP; GRD3; VDBG; VDBP; DBP/GC; HEL-S-51; vitamin D-binding protein; VDB; gc-globulin; vitamin D-binding alpha-globulin; epididymis secretory protein Li 51;
Cat.#:GC-1222HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GC Protein, His-tagged
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Cat.#:GC-1320HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human GC Protein, MYC/DDK-tagged
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Cat.#:GC-4785HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GC Protein, GST-tagged
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Cat.#:gC-1699HTag:
Source (Host):HEK293Species:HSV-1
Product nameRecombinant HSV-1 gC Protein
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Cat.#:GC-1824HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GC protein, His-tagged
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Cat.#:GC-1825HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GC protein, His & T7-tagged
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Cat.#:GC-1826HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GC protein, His & GST-tagged
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Cat.#:GC-200HTag:His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human GC Protein, His-tagged
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Cat.#:GC-224HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human GC
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Cat.#:Gc-1827MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Gc protein, His-tagged
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Cat.#:Gc-1828MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Gc protein, His & GST-tagged
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Cat.#:GC-6254MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GC Protein
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Cat.#:Gc-1829RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Gc protein, His-tagged
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Cat.#:GC-6445CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GC
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Cat.#:GC-689ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GC
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Cat.#:gC-333VTag:His
Source (Host):HEK293Species:HSV-2
Product nameRecombinant HSV-2 gC (Ectodomain) Protein, His-tagged
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Cat.#:GC-198HTag:
Source (Host):Species:Human
Product nameNative Human GC-Globulin
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Cat.#:GC-29857THTag:
Source (Host):Species:Human
Product nameNative Human GC
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Cat.#:GC-524HTag:
Source (Host):Human PlasmaSpecies:Human
Product nameNative Human GC protein
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Cat.#:GC-5995HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GC 293 Cell Lysate
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Cat.#:GC-25HTag:
Source (Host):Species:Human
Product nameHuman Vitamin D Binding Protein Reference Standard
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Cat.#:Gc-93RTag:N/A
Source (Host):Species:Rat
Product nameRat Vitamin D Binding Protein (VDB) Reference Standard
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Involved Pathway

GC involved in several pathways and played different roles in them. We selected most pathways GC participated on our site, such as Metabolism, Metabolism of lipids and lipoproteins, Metabolism of steroid hormones and vitamin D, which may be useful for your reference. Also, other proteins which involved in the same pathway with GC were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Metabolism
ACOT11; GLTPD1; INSIG2; SLC25A11; CBLC-1; GLIPR1; MTP; MED31; MARCKSB; DGUOK
Metabolism of lipids and lipoproteins
CERS4A; PPM1LB; CERS3B; TIAM2; MED9; CEPT1; SPTLC1; FAM213B; APOBB.1; MED25
Metabolism of steroid hormones and vitamin D
PPP1R2; AKR1B15; STARD5; CYP24A1; CYP2R1; GC; CYP27B1; HSD17B11
Vitamin D (calciferol) metabolism
GC
Vitamin D synthesis
GC

Protein Function

GC has several biochemical functions, for example, actin binding, calcidiol binding, vitamin D binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GC itself. We selected most functions GC had, and list some proteins which have the same functions with GC. You can find most of the proteins on our site.
Function
Related Protein
Function actin binding
Related Protein IPP; ABLIM2; CAPZA1B; ACTR2A; WIPF1; MYO1C; MYH15; FSCN2; MYH8; PLS3
Function calcidiol binding
Related Protein GC
Function vitamin D binding
Related Protein CALB1; S100G; GC; VDRA
Function vitamin transporter activity
Related Protein GC; STRA6

Interacting Protein

GC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GC here. Most of them are supplied by our site. Hope this information will be useful for your research of GC.
ACTA1; p29991-pro_0000037941; CCND3; GRB2; SERF2; RIF1; CDC73; PIK3R3; d-mannose; PPP2R2A

GC Related Articles

Sun, RY; Zhuang, HS; et al. An indirect competitive biotin-streptavidin enzyme-linked immunosorbent assay for the determination of dimethyl phthalate (DMP) in milk and milk products. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES 50:275-284(2015).
Wernike, K; Brocchi, E; et al. A novel panel of monoclonal antibodies against Schmallenberg virus nucleoprotein and glycoprotein Gc allows specific orthobunyavirus detection and reveals antigenic differences. VETERINARY RESEARCH 46:-(2015).