ggt1
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  • Official Full Name
  • gamma-glutamyltransferase 1
  • Background
  • The enzyme encoded by this gene catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized and some of which may represent pseudogenes. This gene is classified as type I gamma-glutamyltransferase. Multiple alternatively spliced variants, encoding the same protein, have been identified.
  • Synonyms
  • GGT1; gamma-glutamyltransferase 1; GGT; gamma-glutamyltranspeptidase 1; CD224; D22S672; D22S732; glutamyl transpeptidase; glutathione hydrolase 1; gamma-glutamyl transpeptidase; GTG; GGT 1; MGC96892; MGC96904; MGC96963
Cat.#:GGT1-4876HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GGT1 Protein, GST-tagged
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Cat.#:GGT1-29019THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human GGT1
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Cat.#:GGT1-55HTag:T7/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GGT1 protein, T7/His-tagged
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Cat.#:Ggt1-6880MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ggt1 protein, His & T7-tagged
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Cat.#:GGT1-2523RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GGT1 Protein
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Cat.#:Ggt1-8793RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Ggt1, His tagged
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Cat.#:GGT1-5353HTag:N/A
Source (Host):Human liverSpecies:Human
Product nameNative Human Gamma-Glutamyltransferase 1
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Cat.#:GGT1-8130HTag:N/A
Source (Host):Human liverSpecies:Human
Product nameNative Human Liver Gamma-Glutamyltransferase
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Cat.#:GGT1-8131HTag:N/A
Source (Host):Human liverSpecies:Human
Product nameNative Human Liver Gamma Glutamyl Transpeptidase
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Cat.#:GGT1-371PTag:N/A
Source (Host):Porcine KidneySpecies:Pig
Product nameNative Porcine Gamma-Glutamyltransferase 1
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Cat.#:GGT1-1344RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat GGT1 cell lysate
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Cat.#:GGT1-11HTag:
Source (Host):Species:Human
Product namegamma-Glutamyltransferase Reference Standard
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Involved Pathway

GGT1 involved in several pathways and played different roles in them. We selected most pathways GGT1 participated on our site, such as Taurine and hypotaurine metabolism, Cyanoamino acid metabolism, Glutathione metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with GGT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Taurine and hypotaurine metabolism
GAD1B; GGT5; GAD2; ADOB; CDO1; GGT5A; GGT7; GAD1; ADO; CSAD
Cyanoamino acid metabolism
GGT1A; SHMT1; GGT7; GGT5; GGT1; SHMT2; GBA3; GGT6; GGT5A
Glutathione metabolism
GGCT; GSTA; GSTM5; RRM1; OPLAH; ANPEP; GGCTA; GGT5A; GSTM; GGT1
Arachidonic acid metabolism
AWAT2; CYP2C70; PTGES3; PLA2G12A; CYP4F14; CYP4F22; CYP4A12A; AKR1C6; PLA2G2A; PLA2G5
Metabolic pathways
AKR1C4; PGAM1; FTCD; DGAT1A; PNP5A; POLR2K; ATP5G3A; CKMT2; HEXA; BPNT1

Protein Function

GGT1 has several biochemical functions, for example, gamma-glutamyltransferase activity, glutathione hydrolase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GGT1 itself. We selected most functions GGT1 had, and list some proteins which have the same functions with GGT1. You can find most of the proteins on our site.
Function
Related Protein
Function gamma-glutamyltransferase activity
Related Protein GGT7; GGTLC1; GGT1; GGT6; GGT1A; GGT5A; GGT5
Function glutathione hydrolase activity
Related Protein GGT5; GGT1; GGT6; GGT7
Function protein binding
Related Protein CFL2; Icosl; CALM1; CHRNB2; HIST1H2BI; DDX31; HNRNPAB; SPRR3; G3BP1; UPK3A

Interacting Protein

GGT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GGT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GGT1.
NAMPT; potD