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Official Full Name gamma-glutamyltransferase 1
Background The enzyme encoded by this gene catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized and some of which may represent pseudogenes. This gene is classified as type I gamma-glutamyltransferase. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Synonyms GGT1; gamma-glutamyltransferase 1; GGT; gamma-glutamyltranspeptidase 1; CD224; D22S672; D22S732; glutamyl transpeptidase; glutathione hydrolase 1; gamma-glutamyl transpeptidase; GTG; GGT 1; MGC96892; MGC96904; MGC96963
    • Species :
    • Human
    • Mouse
    • Pig
    • Rat
    • Source :
    • E.coli
    • Human Cell
    • Human Liver
    • Mammalian Cell
    • Porcine Kidney
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GGT1-11H gamma-Glutamyltransferase Reference Standard N/A
    Human GGT1-29019TH Recombinant Human GGT1 Wheat Germ N/A
    Human GGT1-4876H Recombinant Human GGT1 Protein, GST-tagged Wheat Germ GST
    Human GGT1-5353H Native Human Gamma-Glutamyltransferase 1 Human Liver N/A
    Human GGT1-55H Recombinant Human GGT1 protein, T7/His-tagged E.coli T7/His
    Human GGT1-8130H Native Human Liver Gamma-Glutamyltransferase Human Liver N/A
    Human GGT1-8131H Native Human Liver Gamma Glutamyl Transpeptidase Human Liver N/A
    Mouse Ggt1-6880M Recombinant Mouse Ggt1 protein, His & T7-tagged E.coli His/T7
    Rat GGT1-1344RCL Recombinant Rat GGT1 cell lysate Human Cell N/A
    Rat GGT1-2523R Recombinant Rat GGT1 Protein Mammalian Cell His
    Rat Ggt1-8793R Recombinant Rat Ggt1, His tagged Human Cell His
    Pig GGT1-371P Native Porcine Gamma-Glutamyltransferase 1 Porcine Kidney N/A

    GGT1 involved in several pathways and played different roles in them. We selected most pathways GGT1 participated on our site, such as Taurine and hypotaurine metabolism, Cyanoamino acid metabolism, Glutathione metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with GGT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Taurine and hypotaurine metabolism GGT1; GGT5A; GGT7; CSAD; GAD2; BAAT; GAD1B; ADOB; ADO; GAD1
    Cyanoamino acid metabolism SHMT2; GGT5; GGT7; GGT1A; SHMT1; GGT1; GGT6; GGT5A; GBA3
    Glutathione metabolism GSTM3; GSTM7; GPX7; GSTA3; GSTK1; RRM1; MGST1.1; GSTM2; GSTA2; GPX4B
    Arachidonic acid metabolism GGT5; PLA2G6; CYP4F3; CYP2U1; ALOX12B; DPEP1; PTGS2B; AKR1C21; EPHX2; CYP2C8
    Metabolic pathways OTC; AGMAT; AGXTA; ATP6V1H; B3GNT1; CHKB; GNE; P4HA3; CYP4A14; MPST

    GGT1 has several biochemical functions, for example, gamma-glutamyltransferase activity, glutathione hydrolase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GGT1 itself. We selected most functions GGT1 had, and list some proteins which have the same functions with GGT1. You can find most of the proteins on our site.

    Function Related Protein
    gamma-glutamyltransferase activity GGT5A; GGT5; GGT1A; GGT6; GGTLC1; GGT7; GGT1
    glutathione hydrolase activity GGT1; GGT6; GGT5; GGT7
    protein binding INVS; SH3BP1; APLF; CASP1; SOX7; ZNF124; SFN; RIPPLY1; KRTAP4-12; ADAM17

    GGT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GGT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GGT1.

    NAMPT; potD

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