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Recombinant Mouse Ggt1 protein, His & T7-tagged

Cat.No. : Ggt1-6880M
Product Overview : Recombinant Mouse Ggt1 aa. (Asn296~Pro537 (Accession # Q60928)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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  • Gene Information
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Description : This gene encodes gamma-glutamyl transpeptidase, a plasmamembrane-associated enzyme that cleaves the peptide bond between gamma-glutamyl and cysteinyl glycine moieties of glutathione. The encoded protein is autocatalytically processed to generate an enzymatically active heterodimer comprised of heavy and light chains. Mice lacking the encoded protein grow slowly, develop cataracts and have elevated levels of glutathione in plasma and urine. Transgenic overexpression of the encoded protein in mice enhances osteoclastic bone resorption. The mutant alleles termed 'Dwarf grey' and 'Dwarf grey Bayer' in mice are associated with deletions in this gene. A gamma-glutamyl transpeptidase paralog is located adjacent to this gene. Alternative splicing results in multiple transcript variants. Additional transcripts using alternate promoters and differing in 5' UTRs have been described.
Source : E. coli
Species : Mouse
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 30.3kDa.
Protein length : Asn296~Pro537 (Accession # Q60928)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.9.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Ggt1 gamma-glutamyltransferase 1 [ Mus musculus (house mouse) ]
Official Symbol : Ggt1
Synonyms : GGT; dwg; Ggtp; CD224; GGT 1; GGT-1; glutathione hydrolase 1; leukotriene-C4 hydrolase; gamma-glutamyltranspeptidase 1
Gene ID : 14598
mRNA Refseq : NM_001305992.1
Protein Refseq : NP_001292921.1
UniProt ID : Q60928

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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06/13/2022

    Its performance is stable and first-rate, and the manufacturer consistently produces superb products, enabling me to focus on my scientific research.

    05/26/2021

      The quality of the protein reagent is my top consideration, and this reagent does not disappoint.

      07/15/2017

        Its performance is outstanding, and the manufacturer consistently maintains high-quality standards.

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