glrx
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  • Official Full Name
  • glutaredoxin (thioltransferase)
  • Background
  • This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimers disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011]
  • Synonyms
  • GLRX; glutaredoxin (thioltransferase); GRX; GRX1; glutaredoxin-1; TTase-1; thioltransferase-1;
Cat.#:GLRX-4975HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GLRX Protein, GST-tagged
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Cat.#:Glrx-631MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Glrx Protein, His-tagged
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Cat.#:GLRX-166HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GLRX, His-tagged
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Cat.#:GLRX-27691THTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GLRX
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Cat.#:GLRX-368HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GLRX, His tagged
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Cat.#:GLRX-2570RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GLRX Protein
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Cat.#:GLRX-1874RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GLRX Protein, His-tagged
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Cat.#:GLRX-6716CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GLRX
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Cat.#:GLRX-1476ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GLRX
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Cat.#:GLRX-138HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Glutaredoxin-1
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Cat.#:GLRX-5898HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human GLRX 293 Cell Lysate
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Involved Pathway

GLRX involved in several pathways and played different roles in them. We selected most pathways GLRX participated on our site, such as Metabolism, Metabolism of nucleotides, Synthesis and interconversion of nucleotide di- and triphosphates, which may be useful for your reference. Also, other proteins which involved in the same pathway with GLRX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Metabolism
FAM213B; COX18; SLC35B2; MED19; SLC25A13; FABP11B; SACM1LA; CD320; SLC26A1; NOSIP
Metabolism of nucleotides
NUDT5; NUDT16; GLRX; ADSSL1; AK7A; AK8; DPYDA.1; TYMP; ADSL; DPYS
Synthesis and interconversion of nucleotide di- and triphosphates
AK8; GRX2; AK7; DTYMK; GLRX; AK7A
ascorbate recycling (cytosolic)
GLRX

Protein Function

GLRX has several biochemical functions, for example, electron carrier activity, glutathione disulfide oxidoreductase activity, glutathione oxidoreductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GLRX itself. We selected most functions GLRX had, and list some proteins which have the same functions with GLRX. You can find most of the proteins on our site.
Function
Related Protein
Function electron carrier activity
Related Protein NDUFS6; IDO1; GLDC; NCF2; ACOXL; DERL3; GRXCR1; COX7A1; GLRX; AOX4
Function glutathione disulfide oxidoreductase activity
Related Protein GLRX2; GLRX
Function glutathione oxidoreductase activity
Related Protein GLRX
Function protein N-terminus binding
Related Protein PPP1CC; ALG2; SCT; NTSR1; HAX1; MORF4L1; CSNK2A2; GTF2H2; VWF; PDLIM5

Interacting Protein

GLRX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLRX here. Most of them are supplied by our site. Hope this information will be useful for your research of GLRX.
MMP23A; GOT2; CASP3; AQP5