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GLRX

  • Official Full Name

    glutaredoxin (thioltransferase)

  • Overview

    This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimers disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011]
  • Synonyms

    GLRX; glutaredoxin (thioltransferase); GRX; GRX1; glutaredoxin-1; TTase-1; thioltransferase-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GLRX-78H Recombinant Human GLRX N/A
Human GLRX-138H Recombinant Human Glutaredoxin-1 E.coli N/A
Human GLRX-368H Recombinant Human GLRX, His tagged E.coli N/A
Human GLRX-27691TH Recombinant Human GLRX E.coli N/A
Human GLRX-166H Recombinant Human GLRX protein, His-tagged E.coli His Met1-Gln106
Human GLRX-5898HCL Recombinant Human GLRX 293 Cell Lysate HEK293 N/A
Human GLRX-139H Recombinant Human GLRX Protein, His-tagged E.coli His
Human GLRX-014H Recombinant Human GLRX Protein E.coli
Human GLRX-4975H Recombinant Human GLRX Protein, GST-tagged Wheat Germ GST
Human GLRX-012H Recombinant Human GLRX Protein E.coli
Human GLRX-5346HF Recombinant Full Length Human GLRX Protein, GST-tagged In Vitro Cell Free System GST 106 amino acids
Human GLRX-015H Recombinant Human GLRX Protein E.coli
Human GLRX-154H Recombinant Human GLRX Protein
Human GLRX-4206H Recombinant Human GLRX Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GLRX-1901HFL Recombinant Full Length Human GLRX Protein, C-Flag-tagged Mammalian cells Flag
Human GLRX-5205H Recombinant Human GLRX Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GLRX-988H Recombinant Human GLRX Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human GLRX-2968H Recombinant Human GLRX protein, GST-tagged E.coli GST 1-106aa
Human GLRX-988H-B Recombinant Human GLRX Protein Pre-coupled Magnetic Beads HEK293
Mouse Glrx-3229M Recombinant Mouse Glrx Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Glrx-631M Recombinant Mouse Glrx Protein, His-tagged E.coli His Ala2~Leu107
Rat GLRX-2570R Recombinant Rat GLRX Protein Mammalian Cell His
Rat GLRX-2225R-B Recombinant Rat GLRX Protein Pre-coupled Magnetic Beads HEK293
Rat GLRX-2225R Recombinant Rat GLRX Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GLRX-1874R Recombinant Rhesus monkey GLRX Protein, His-tagged Mammalian Cell His
Rhesus Macaque GLRX-1694R Recombinant Rhesus Macaque GLRX Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GLRX-1694R-B Recombinant Rhesus Macaque GLRX Protein Pre-coupled Magnetic Beads HEK293
Zebrafish GLRX-1476Z Recombinant Zebrafish GLRX Mammalian Cell His
Chicken GLRX-6716C Recombinant Chicken GLRX Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

GLRX involved in several pathways and played different roles in them. We selected most pathways GLRX participated on our site, such as Metabolism, Metabolism of nucleotides, Synthesis and interconversion of nucleotide di- and triphosphates, which may be useful for your reference. Also, other proteins which involved in the same pathway with GLRX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MetabolismSULT1C2;SULT1B1;SLC25A2;GPC5A;PDPR;MED6;CPNE7;ATP5L;AGL
Metabolism of nucleotidesADA;ADAL;NUDT5;NUDT16;ADSS;AK7A;TYMP;ADSSL1;PROZA
Synthesis and interconversion of nucleotide di- and triphosphatesGRX2;DTYMK;AK8;GLRX;AK7;AK7A
ascorbate recycling (cytosolic)

GLRX has several biochemical functions, for example, electron carrier activity, glutathione disulfide oxidoreductase activity, glutathione oxidoreductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GLRX itself. We selected most functions GLRX had, and list some proteins which have the same functions with GLRX. You can find most of the proteins on our site.

Function Related Protein
electron carrier activityUGDH;SDHC;DERL3;GPX2;NQO2;CYP1A2;HAAO;TSTA3;ACOX3
glutathione disulfide oxidoreductase activityGLRX2;GLRX
glutathione oxidoreductase activity
protein N-terminus bindingSYNGR3;PEX5;PPP1CC;APTX;SLC6A3;EIF3E;NTSR1;GTF2H3;MECP2

GLRX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLRX here. Most of them are supplied by our site. Hope this information will be useful for your research of GLRX.

MMP23A; GOT2; CASP3; AQP5

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