• Official Full Name
  • glucocorticoid modulatory element binding protein 1
  • Background
  • This gene encodes a member of KDWK gene family which associates with GMEB2 protein. The GMEB1-GMEB2 complex is essential for parvovirus DNA replication. Studies in rat for a similar gene suggest that this genes role is to modulate the transactivation of the glucocorticoid receptor when it is bound to glucocorticoid response elements. Two alternative spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Feb 2011]
  • Synonyms
  • GMEB1; glucocorticoid modulatory element binding protein 1; PIF96; P96PIF; glucocorticoid modulatory element-binding protein 1; GMEB-1; PIF p96; DNA-binding protein p96PIF; parvovirus initiation factor p96;
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GMEB1 Protein, GST-tagged
Source (Host):Sf9 cellsSpecies:Human
Product nameRecombinant Human GMEB1 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GMEB1 Protein
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GMEB1
Source (Host):Species:Human
Product nameRecombinant Human GMEB1 293 Cell Lysate

Protein Function

GMEB1 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, metal ion binding, transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GMEB1 itself. We selected most functions GMEB1 had, and list some proteins which have the same functions with GMEB1. You can find most of the proteins on our site.
Related Protein
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein BATF3; SNAI3; ZNF502; NFATC3; ZGPAT; FOSB; MYB; ZNF486; ZNF718; TLX1
Function metal ion binding
Related Protein HDAC9; PPP1CA; ZNF750; HGD; ZIK1; IHHB; CACNA2D4; ADI1; SIAH2L; CAT
Function transcription coactivator activity
Related Protein NFKBIB; PRRX1; SP100; NR5A1; E4F1; BCL10; ABRA; ASXL1; SETD3; NPAT
Function transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
Related Protein TP53; PATZ1; HOXC13; POU2F3; IRF1; MYBL1; BATF; FOXC2; RELA; ZIC1

Interacting Protein

GMEB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GMEB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GMEB1.