Recombinant Human GMEB1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: GMEB1-2804H
• Product Overview: GMEB1 MS Standard C13 and N15-labeled recombinant protein (NP_077808) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of KDWK gene family which associates with GMEB2 protein. The GMEB1-GMEB2 complex is essential for parvovirus DNA replication. Studies in rat for a similar gene suggest that this gene's role is to modulate the transactivation of the glucocorticoid receptor when it is bound to glucocorticoid response elements. Three alternative spliced transcript variants encoding different isoforms exist.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 61.3 kDa
• AA Sequence: MANAEVSVPVGDVVVVPTEGNEGEN PEDTKTQVILQLQPVQQGIYEAGSE NNTAVVAVETHTIHKIEEGIDTGTI EANEDMEIAYPITCGESKAILLWKK FVCPGINVKCVKFNDQLISPKHFVH LAGKSTLKDWKRAIRLGGIMLRKMM DSGQIDFYQHDKVCSNTCRSTKFDL LISSARAPVPGQQTSVVQTPTSADG SITQIAISEESMEEAGLEWNSALTA AVTMATEEGVKKDSEEISEDTLMFW KGIADVGLMEEVVCNIQKEIEELLR GVQQRLIQAPFQVTDAAVLNNVAHT FGLMDTVKKVLDNRRNQVEQGEEQF LYTLTDLERQLEEQKKQGQDHRLKS QTVQNVVLMPVSTPKPPKRPRLQRP ASTTVLSPSPPVQQPQFTVISPITI TPVGQSFSMGNIPVATLSQGSSPVT VHTLPSGPQLFRYATVVSSAKSSSP DTVTIHPSSSLALLSSTAMQDGSTL GNMTTMVSPVELVAMESGLTSAIQA VESTSEDGQTIIEIDPAPDPEAEDT EGKAVILETELRTEEKVVAEMEEHQ HQVHNVEIVVLEDTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: GMEB1 glucocorticoid modulatory element binding protein 1 [ Homo sapiens (human) ]
• Official Symbol: GMEB1
• Synonyms: GMEB1; glucocorticoid modulatory element binding protein 1; glucocorticoid modulatory element-binding protein 1; P96PIF; PIF96; GMEB-1; PIF p96; DNA-binding protein p96PIF; parvovirus initiation factor p96
• Gene ID: 10691
• mRNA Refseq: NM_024482
• Protein Refseq: NP_077808
• MIM: 604409
• UniProt ID: Q9Y692