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Official Full Name guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
Background Phototransduction in rod and cone photoreceptors is regulated by groups of signaling proteins. The encoded protein is thought to play a crucial role in cone phototransduction. It belongs to the G protein gamma family and localized specifically in cones. Several transcript variants encoding the same protein have been found for this gene.
Synonyms GNGT2; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2; GNG9; G GAMMA 8; G gamma 9; G GAMMA C; G protein cone gamma 8 subunit; gamma T2 subunit; GNG8; GNGT8; guanine nucleotide binding protein (G protein), gamma transducing; Guanine nucleotide binding protein G; guanine nucleotide binding protein gamma 9; guanine nucleotide binding protein gamma transducing activity; IG; Ogamma T2 subunit precursor; SG; G-gamma-9; g gamma-C; gamma-T2 subunit; OTTHUMP00000220018; OTTHUMP00000220019; OTTHUMP00000220020; OTTHUMP00000220021; OTTHUMP00000220022; guanine nucleotide bindin; G-GAMMA-8; G-GAMMA-C
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Gngt2-1040M Recombinant Mouse Gngt2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human GNGT2-1503H Recombinant Human GNGT2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human GNGT2-13367H Recombinant Human GNGT2, GST-tagged E.coli GST
    Human GNGT2-5077H Recombinant Human GNGT2 Protein, GST-tagged Wheat Germ GST
    Human GNGT2-5849HCL Recombinant Human GNGT2 293 Cell Lysate HEK293 N/A
    Rhesus Macaque GNGT2-1908R Recombinant Rhesus monkey GNGT2 Protein, His-tagged Mammalian Cell His
    Chicken GNGT2-5602C Recombinant Chicken GNGT2 Mammalian Cell His

    GNGT2 involved in several pathways and played different roles in them. We selected most pathways GNGT2 participated on our site, such as Ras signaling pathway, Chemokine signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNGT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ras signaling pathway PDGFRB; FGFR1; PLA2G12B; Fasl; PAK6; PLA1A; GNG5; FGFR3; PLA2G4C; GRIN2B
    Chemokine signaling pathway GSK3A; LYN; CCR1; GNAI1; CXCR6; Cxcl15; CX3CR1; DOCK2; Adcy4; CCL4
    PIK-Akt signaling pathway FGF3; OSM; PIK3CB; PDGFC; MTOR; FGF12; Ifna15; THBS3; SYK; IL2RB
    Circadian entrainment PRKACG; GNG3; ADCYAP1R1; CAMK2D; PRKCG; GNG13; GNB3; GRIA1; GNG11; CACNA1H
    Retrograde endocannabinoid signaling GNG2; ITPR1; PRKCA; NAPEPLD; GABRQ; GRIA2; GABRR3; GABRG2; GABRD; PLCB4
    Glutamatergic synapse ITPR1; SHANK3; GRIA3; PLA2G4F; PLA2G4A; SLC1A7; HOMER3; SLC1A2; GNB4; PLA2G4D
    Cholinergic synapse MAPK1; KCNQ1; AKT2; CHRNA4; PRKACB; GNAI3; CAMK4; GNB2; CREB3L3; KCNJ12
    Serotonergic synapse PLCB4; CYP2C50; PRKCB; GNAI3; HTR3C; SLC18A1; HTR3B; PTGS1; CYP2J5; ALOX12B
    GABAergic synapse GABRB1; GNG2; GABRG3; GNG7; SLC6A13; GABRP; GNG10; GNG8; SLC38A2; GABRG2
    Dopaminergic synapse PLCB2; CALM4; GRIA4; KCNJ5; PPP2R5B; ARRB2; CREB3L3; CLOCK; PRKACG; GNG2
    Morphine addiction GABRP; GABRR2; PRKCG; GABRG3; PRKACG; GNG12; GNB4; Adcy4; GNG5; GNB3
    Pathways in cancer FADD; FGF13; NFKBIA; TRAF2; LAMA4; PAX8; NKX3-1; Fasl; LAMB4; BDKRB1

    GNGT2 has several biochemical functions, for example, GTPase activity, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNGT2 itself. We selected most functions GNGT2 had, and list some proteins which have the same functions with GNGT2. You can find most of the proteins on our site.

    Function Related Protein
    GTPase activity RAB8A; RAB31; RAB3AB; GIMAP7; EEF2A.1; EEF1A1A; DNM1L; RAB11BB; TUBD1; GTPBP10
    signal transducer activity VMN1R44; OLFR477; PLCD3; GNG3; TAAR12I; HTR5AL; ACKR3B; EEF1D; IRS1; GRM8B

    GNGT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNGT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNGT2.

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