gngt2
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  • Official Full Name
  • guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
  • Background
  • Phototransduction in rod and cone photoreceptors is regulated by groups of signaling proteins. The encoded protein is thought to play a crucial role in cone phototransduction. It belongs to the G protein gamma family and localized specifically in cones. Several transcript variants encoding the same protein have been found for this gene.
  • Synonyms
  • GNGT2; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2; GNG9; G GAMMA 8; G gamma 9; G GAMMA C; G protein cone gamma 8 subunit; gamma T2 subunit; GNG8; GNGT8; guanine nucleotide binding protein (G protein), gamma transducing; Guanine nucleotide binding protein G; guanine nucleotide binding protein gamma 9; guanine nucleotide binding protein gamma transducing activity; IG; Ogamma T2 subunit precursor; SG; G-gamma-9; g gamma-C; gamma-T2 subunit; OTTHUMP00000220018; OTTHUMP00000220019; OTTHUMP00000220020; OTTHUMP00000220021; OTTHUMP00000220022; guanine nucleotide bindin; G-GAMMA-8; G-GAMMA-C
Cat.#:GNGT2-5077HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GNGT2 Protein, GST-tagged
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Cat.#:GNGT2-13367HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GNGT2, GST-tagged
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Cat.#:GNGT2-1908RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GNGT2 Protein, His-tagged
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Cat.#:GNGT2-5602CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GNGT2
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Cat.#:GNGT2-5849HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GNGT2 293 Cell Lysate
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Involved Pathway

GNGT2 involved in several pathways and played different roles in them. We selected most pathways GNGT2 participated on our site, such as Ras signaling pathway, Chemokine signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNGT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ras signaling pathway
BCL2L1; RALBP1; PRKCG; PAK2; FGF17; PDGFA; PRKCA; RHOA; TBK1; RASAL1
Chemokine signaling pathway
CXCL16; CCR7; GNGT2; CXCR4; FGR; RELA; CCL26; STAT5B; PIK3CA; CXCL8
PIK-Akt signaling pathway
LAMA5; LAMB2; Kitl; YWHAH; GNGT2; VEGFA; HGF; MLST8; PDGFRA; IL4
Circadian entrainment
GUCY1B3; CACNA1G; GNG10; GRIA4; PLCB4; CALML3; CAMK2A; CAMK2D; PER2; GNAI2
Retrograde endocannabinoid signaling
MAPK8; MAPK1; GABRG1; GABRA4; GNB4; MAPK10; GABRB3; GNG4; PRKACG; GABRE
Glutamatergic synapse
GNAO1; GRIN2D; PPP3R1; GNAI1; GRM3; GNAQ; ITPR3; PPP3CB; GLS2; GRM8
Cholinergic synapse
GNB2; KRAS; PIK3CD; PIK3R2; PIK3R5; CREB5; CHRM5; CHRNA6; FOS; KCNJ6
Serotonergic synapse
GNG11; MAOA; ALOX12E; PLA2G4D; GNG13; PLA2G4F; CYP2C37; ALOX15; GNB3; GNG12
GABAergic synapse
SLC6A1; GNAI1; GABRA3; GNG5; GNGT2; GABARAPL2; GABRA4; NSF; GNB4; GNAI3
Dopaminergic synapse
PPP2R5D; ITPR3; ARRB2; GSK3B; CALM3; CREB5; GRIN2A; GRIA2; DRD5; CALM2
Morphine addiction
PDE4D; GNGT2; PDE4B; PRKACG; GNAI1; GABRR1; GNB3; GABRA4; GABRG3; GNAS
Alcoholism
DRD1A; NPY; HIST1H4A; H3F3C; FOSB; HDAC6; SHC3; SLC29A1; HIST1H3G; ATF4
Pathways in cancer
GNAI1; AKT1; TGFA; GSTP1; FLT3; PTGER3; CTBP2; PLCG2; GSK3B; CCND1

Protein Function

GNGT2 has several biochemical functions, for example, GTPase activity, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNGT2 itself. We selected most functions GNGT2 had, and list some proteins which have the same functions with GNGT2. You can find most of the proteins on our site.
Function
Related Protein
Function GTPase activity
Related Protein RALAA; DIRAS1; MX2; GBP5; RAB5AA; CDC42; GBP2; GBP6; GNL3; NOA1
Function signal transducer activity
Related Protein TAS2R109; GNA13B; CCR1L1; NDFIP1; PLCB2; GHRHRL; CHRM5B; PLCD1B; GNA11; SH2B2