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GNGT2

Official Full Name

guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
Overview

Phototransduction in rod and cone photoreceptors is regulated by groups of signaling proteins. The encoded protein is thought to play a crucial role in cone phototransduction. It belongs to the G protein gamma family and localized specifically in cones. Several transcript variants encoding the same protein have been found for this gene.
Synonyms

GNGT2; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2; GNG9; G GAMMA 8; G gamma 9; G GAMMA C; G protein cone gamma 8 subunit; gamma T2 subunit; GNG8; GNGT8; guanine nucleotide binding protein (G protein), gamma transducing; Guanine nucleotide binding protein G; guanine nucleotide binding protein gamma 9; guanine nucleotide binding protein gamma transducing activity; IG; Ogamma T2 subunit precursor; SG; G-gamma-9; g gamma-C; gamma-T2 subunit; OTTHUMP00000220018; OTTHUMP00000220019; OTTHUMP00000220020; OTTHUMP00000220021; OTTHUMP00000220022; guanine nucleotide bindin; G-GAMMA-8; G-GAMMA-C;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rhesus Macaque

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
MYC
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GNGT2-13367H	Recombinant Human GNGT2, GST-tagged	E.coli	GST	1-69a.a.	$319 / 25ug
Human	GNGT2-5849HCL	Recombinant Human GNGT2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	GNGT2-5077H	Recombinant Human GNGT2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GNGT2-1503H	Recombinant Human GNGT2 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	GNGT2-5394HF	Recombinant Full Length Human GNGT2 Protein, GST-tagged	In Vitro Cell Free System	GST	69 amino acids	Inquiry
Mouse	Gngt2-1040M	Recombinant Mouse Gngt2 Protein, MYC/DDK-tagged	HEK293T	MYC/DDK		Inquiry
Rhesus Macaque	GNGT2-1908R	Recombinant Rhesus monkey GNGT2 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	GNGT2-1728R	Recombinant Rhesus Macaque GNGT2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	GNGT2-1728R-B	Recombinant Rhesus Macaque GNGT2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	GNGT2-5602C	Recombinant Chicken GNGT2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

GNGT2 involved in several pathways and played different roles in them. We selected most pathways GNGT2 participated on our site, such as Ras signaling pathway, Chemokine signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNGT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ras signaling pathway	AKT1;NF1;FGFR3;FGF3;RGL1;INS1;FGFR2;PLA2G3;GNGT2
Chemokine signaling pathway	CXCL8;BRAF;FOXO3;CCL8;PTK2B;VAV1;GNGT2;KRAS;CRKL
PIK-Akt signaling pathway	EIF4E1B;IKBKB;MLST8;BAD;INS2;BCL2L1;MAPK1;IL2RA;FN1
Circadian entrainment	GNB4;KCNJ5;RPS6KA5;MAPK3;RASD1;GRIN1;PLCB2;GNB2;ADCYAP1R1
Retrograde endocannabinoid signaling	GABRB3;GNG8;GNG4;SLC17A6;GABRE;GNB4;GNG7;MAPK11;GABRB2
Glutamatergic synapse	SHANK1;PRKCB;PRKCG;SHANK2;ITPR3;HOMER1;GNAS;GRIK3;PLA2G4F
Cholinergic synapse	GNAI1;KCNQ5;BCL2;GNB3;GNAQ;PRKACA;KCNJ2;CREB3L4;CAMK2D
Serotonergic synapse	SLC18A2;GNG5;SLC6A4;GNAQ;ALOX15;HTR1E;GABRB3;TRPC1;CYP2C70
GABAergic synapse	SLC38A3;GNB3;GABRA1;GLS;GABRB1;PRKACB;GABRR2;GABRA2;HAP1
Dopaminergic synapse	CAMK2D;PPP3CB;FOS;GNAI1;CALM3;MAPK8;PPP1CB;CAMK2B;DRD5
Alcoholism	HIST1H2AH;HIST1H2AI;HDAC5;GNAS;CALM4;CREB3;HIST1H2BL;HIST1H4B;HIST1H3A
Pathways in cancer	PIAS2;FGF18;SKP2;MMP2;CCND1;DAPK1;GNB3;SLC2A1;PRKACB

GNGT2 has several biochemical functions, for example, GTPase activity, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNGT2 itself. We selected most functions GNGT2 had, and list some proteins which have the same functions with GNGT2. You can find most of the proteins on our site.

Function	Related Protein
GTPase activity	GNA13B;ARL8B;RAB41;RAB15;RHOB;RAB1;TUFM;RAB12;RAB2A
signal transducer activity	PLCB1;RGS11;IRS1;RGS7;OLFR498;CRKL;APLNRB;OLFR469;TRIM55

GNGT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNGT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNGT2.