gngt2
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  • Official Full Name
  • guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
  • Background
  • Phototransduction in rod and cone photoreceptors is regulated by groups of signaling proteins. The encoded protein is thought to play a crucial role in cone phototransduction. It belongs to the G protein gamma family and localized specifically in cones. Several transcript variants encoding the same protein have been found for this gene.
  • Synonyms
  • GNGT2; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2; GNG9; G GAMMA 8; G gamma 9; G GAMMA C; G protein cone gamma 8 subunit; gamma T2 subunit; GNG8; GNGT8; guanine nucleotide binding protein (G protein), gamma transducing; Guanine nucleotide binding protein G; guanine nucleotide binding protein gamma 9; guanine nucleotide binding protein gamma transducing activity; IG; Ogamma T2 subunit precursor; SG; G-gamma-9; g gamma-C; gamma-T2 subunit; OTTHUMP00000220018; OTTHUMP00000220019; OTTHUMP00000220020; OTTHUMP00000220021; OTTHUMP00000220022; guanine nucleotide bindin; G-GAMMA-8; G-GAMMA-C
Cat.#:GNGT2-5077HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GNGT2 Protein, GST-tagged
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Cat.#:GNGT2-13367HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GNGT2, GST-tagged
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Cat.#:GNGT2-1908RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GNGT2 Protein, His-tagged
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Cat.#:GNGT2-5602CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GNGT2
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Cat.#:GNGT2-5849HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GNGT2 293 Cell Lysate
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Involved Pathway

GNGT2 involved in several pathways and played different roles in them. We selected most pathways GNGT2 participated on our site, such as Ras signaling pathway, Chemokine signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNGT2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ras signaling pathway
ABL2; GNG5; GAB1; SHC4; MAPK9; IGF1R; CALM4; PIK3CA; GNG8; AKT1
Chemokine signaling pathway
CCR8; PLCB2; IKBKB; CCL6; PTK2B; FOXO3; PLCB3; NCF1; NRAS; Ccl21a
PIK-Akt signaling pathway
VEGFC; YWHAB; Reln; NFKB1; IFNA14; RPS6KB1; PDPK1; COL6A4; ANGPT1; KRAS
Circadian entrainment
GNG3; GUCY1A3; GNAI2; CALM3; MTNR1B; GNAQ; RYR1; GRIN1; PLCB1; PLCB4
Retrograde endocannabinoid signaling
GABRB2; FAAH; GNB2; GABRE; GNG11; GRM5; RIMS1; GABRD; GNG7; GNG2
Glutamatergic synapse
HOMER3; SHANK2; PPP3CC; HOMER2; GRIA2; SLC1A1; PLA2G4F; GRIK5; GNAO1; PRKCB
Cholinergic synapse
PRKACA; AKT1; MAPK1; CHRNA3; PLCB2; PIK3R2; PIK3R5; CHRNA4; KRAS; CHRNA7
Serotonergic synapse
PTGS1; ARAF; GNG7; GNG5; GNG8; HTR3C; GNAI1; GNB2; CYP2C39; PTGS2
GABAergic synapse
GABRA1; SLC38A5; GNB4; GNB2; GNAO1; GABRD; SLC6A1; GNGT1; PRKACB; GABRB3
Dopaminergic synapse
CREB3L4; CALY; GRIN2A; GNAQ; GNB2; GNG8; GNG10; MAPK8; PPP3CB; MAPK13
Morphine addiction
PRKACG; PDE4C; GABRQ; GABRR2; LOC100328615; PDE3A; PRKACB; ARRB1; GNGT1; GABRA2
Alcoholism
HIST1H3D; GM14482; NPY; HIST1H2BE; HDAC3; HDAC6; NRAS; ADORA2B; HIST2H2BB; HIST3H3
Pathways in cancer
TRAF3; RET; ARHGEF1; FLT3LG; HDAC2; PGF; PLCB2; FGF10; MMP1; WNT7A

Protein Function

GNGT2 has several biochemical functions, for example, GTPase activity, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNGT2 itself. We selected most functions GNGT2 had, and list some proteins which have the same functions with GNGT2. You can find most of the proteins on our site.
Function
Related Protein
Function GTPase activity
Related Protein IFT27; RAB18A; RAB11A; IRGF1; TUBB6; IFT22; RASL10A; GNL2; GTPBP3; RALAB
Function signal transducer activity
Related Protein GNA11A; VMN1R47; GNB5; ADCYAP1R1A; ADRB2B; HCAR1-2; MIER1B; CC2D1A; VMN2R116; TAAR8B