Recombinant Human GNGT2, GST-tagged

• Cat.No.: GNGT2-13367H
• Product Overview: Recombinant Human GNGT2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-69a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 [ Homo sapiens ]
• Official Symbol: GNGT2
• Synonyms: GNGT2; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2; GNG9; G-gamma-9; g gamma-C; gamma-T2 subunit; G protein cone gamma 8 subunit; guanine nucleotide binding protein gamma 9; guanine nucleotide binding protein gamma transducing activity polypeptide 2; GNG8; GNGT8; G-GAMMA-8; G-GAMMA-C
• Gene ID: 2793
• mRNA Refseq: NM_001198754
• Protein Refseq: NP_001185683
• MIM: 139391
• UniProt ID: O14610
• Chromosome Location: 17q21
• Pathway: ADP signalling through P2Y purinoceptor 1, organism-specific biosystem; ADP signalling through P2Y purinoceptor 12, organism-specific biosystem; Activation of G protein gated Potassium channels, organism-specific biosystem; Activation of GABAB receptors, organism-specific biosystem; Activation of Kainate Receptors upon glutamate binding, organism-specific biosystem; Aquaporin-mediated transport, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem
• Function: GTPase activity; GTPase activity; signal transducer activity