• Official Full Name
  • glycoprotein A33 (transmembrane)
  • Background
  • The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
  • Synonyms
  • GPA33; glycoprotein A33 (transmembrane); cell surface A33 antigen; A33; transmembrane glycoprotein A33; MGC129986; MGC129987
Source (Host):HEK293Species:Human
Product nameRecombinant human GPA33 Protein, His-tagged, Biotinylated
Source (Host):HEK293Species:Human
Product nameRecombinant Human GPA33 Protein, MYC/DDK-tagged
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GPA33 Protein, GST-tagged
Source (Host):HEK293Species:Human
Product nameRecombinant Human GPA33, C13&N15-labeled
Source (Host):HEK293Species:Human
Product nameRecombinant Human GPA33, His tagged
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Gpa33, His tagged
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Gpa33 protein, His & T7-tagged
Source (Host):HEK293Species:Human
Product nameRecombinant Human GPA33 cell lysate
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse GPA33 cell lysate

Protein Function

GPA33 has several biochemical functions, for example, protein binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPA33 itself. We selected most functions GPA33 had, and list some proteins which have the same functions with GPA33. You can find most of the proteins on our site.
Related Protein
Function protein binding
Related Protein BAZ2A; TSPO; CPNE1; KAT5; BRAF; DTL; INVS; SIP1; DENR; STX12
Function receptor activity
Related Protein NLGN3; SLC20A1; RPA1; CALCR; TLR1; MCC; CUL5; PVR; CUBN; VMN1R50

Interacting Protein

GPA33 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPA33 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPA33.
POT1; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate

GPA33 Related Articles

Tome-Amat, J; Menendez-Mendez, A; et al. Production and characterization of scFvA33T1, an immunoRNase targeting colon cancer cells. FEBS JOURNAL 279:3022-3032(2012).
Carreras-Sangra, N; Tome-Amat, J; et al. Production and characterization of a colon cancer-specific immunotoxin based on the fungal ribotoxin -sarcin. PROTEIN ENGINEERING DESIGN & SELECTION 25:425-435(2012).