Recombinant Human GPA33 protein, His-Avi-tagged, Biotinylated

• Cat.No.: GPA33-795HB
• Product Overview: Biotinylated Recombinant Human GPA33/A33 Protein Protein is expressed from mammalian with a poly-His and Avi tag at the C-terminal. It contains Ile22-Val235.

Specification

• Description: Glycoprotein A33 (GPA33) is also known as Cell surface A33 antigen, is a single-pass type I membrane protein which is expressed in normal gastrointestinal epithelium and in 95% of colon cancers. GPA33 The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain characteristic of the CD2 subgroup of the immunoglobulin (Ig)superfamily, which contains. GPA33 may play a role in cell-cell recognition and signaling.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22μm filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 26.5 kDa. Due to glycosylation, the protein migrates to 28-40 kDa based on Bis-Tris PAGE result.
• Protein length: Ile22-Val235
• Endotoxin: Less than 0.05 EU per μg by the LAL method.
• Purity: >95% as determined by Bis-Tris PAGE; >95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: GPA33
• Official Symbol: GPA33
• Synonyms: Cell surface A33 antigen; Glycoprotein A33; GPA33
• Gene ID: 10223
• mRNA Refseq: NM_005814.3
• Protein Refseq: NP_005805.1
• MIM: 602171
• UniProt ID: Q99795