GSTO2 Protein, glutathione S-transferase omega 2


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Official Full Name glutathione S-transferase omega 2
Background The protein encoded by this gene is an omega class glutathione S-transferase (GST). GSTs are involved in the metabolism of xenobiotics and carcinogens. Four transcript variants encoding different isoforms have been found for this gene.
Synonyms GSTO2; glutathione S-transferase omega 2; glutathione S-transferase omega-2; bA127L20.1; Glutathione S transferase like protein; Glutathione S transferase omega 2; GSTO 2; GSTO-2; GSTO2_HUMAN; glutathione-S-transferase-like protein; bA127L20.1 (novel glutathione-S-transferase)
    • Species :
    • Human
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GSTO2-15855H Recombinant Human GSTO2, His-tagged E.coli His
    Human GSTO2-1961H Recombinant Human Glutathione S-Transferase Omega 2, His-tagged E.coli His
    Human GSTO2-4426H Recombinant Human GSTO2 Protein, GST-tagged Wheat Germ GST
    Human GSTO2-5710HCL Recombinant Human GSTO2 293 Cell Lysate HEK293 N/A
    Rhesus Macaque GSTO2-1996R Recombinant Rhesus monkey GSTO2 Protein, His-tagged Mammalian Cell His
    Zebrafish GSTO2-1759Z Recombinant Zebrafish GSTO2 Mammalian Cell His

    GSTO2 involved in several pathways and played different roles in them. We selected most pathways GSTO2 participated on our site, such as Biological oxidations, Chemical carcinogenesis, Drug metabolism - cytochrome P450, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSTO2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Biological oxidations ABHD14B; CYP2W1; NAT2; CYP3A7-CYP3AP1; CYP1A2; Sult2a2; CYP4F11; CYP2C8; UGT1B2; CYP1A1
    Chemical carcinogenesis ADH2-1; CYP3A4; GSTP1; CYP3A41B; EPHX1; CYP2C55; ARNT; GSTM4; PTGS2; CYP3A7
    Drug metabolism - cytochrome P450 CYP2B6; CYP2C19; ADH6; ADH2-2; ADH7; GSTK1; CYP2C8; CYP2A6; ADH2-1; GSTO2
    Glutathione conjugation GSTO2; GSTK1; GGTLC1; GGT6; AKR1A1
    Glutathione metabolism SMS; G6PD; GSTO2; GGT5A; MGST1.1; ANPEP; MGST3; IDH2; GSS; GSTP1
    Metabolism ARL2BP; SLC26A1; CPOX; OAZ3; CLPS; AK8; HELZ2; AADAC; CYP2F1; CHST14
    Metabolism of vitamins and cofactors SLC25A32A; SLC46A1; CD320; CBLC-1; GPHN; SLC52A3; NAMPT; GPHNA; SLC25A32; CTRB1
    Metabolism of water-soluble vitamins and cofactors TCN1; CTRC; PDZD11; CYB5A; SLC25A32; SLC52A3; KCNG4; SLC25A32B; ELA2; SLC25A16

    GSTO2 has several biochemical functions, for example, glutathione dehydrogenase (ascorbate) activity, glutathione transferase activity, methylarsonate reductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GSTO2 itself. We selected most functions GSTO2 had, and list some proteins which have the same functions with GSTO2. You can find most of the proteins on our site.

    Function Related Protein
    glutathione dehydrogenase (ascorbate) activity GSTO1; GSTO2
    glutathione transferase activity GSTO1; GSTAL; GSTT2B; GDAP1; LTC4S; GSTM3; GSTM2; GSTA3; GSTM5; GDAP1L1
    methylarsonate reductase activity GSTO2; GSTO1
    oxidoreductase activity APEX1; CMAH; CYP1A; QDPRA; CYP2K22; AIFM4; FRRS1; GSTO1; CYP2C19; AKR1C21
    protein binding NR4A1; GAS6; HMOX2; ATRX; GIPC2; WIBG; DHH; TEAD3; SOCS4; APOA1BP

    GSTO2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSTO2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSTO2.

    TFAP2A; MUM1

    Glisic, B; Mihaljevic, I; et al. Characterization of glutathione-S-transferases in zebrafish (Danio rerio). AQUATIC TOXICOLOGY 158:50-62(2015).
    Azizian-Farsani, F; Rafiei, G; et al. Impact of Sodium Arsenite on Chromosomal Aberrations With Respect to Polymorphisms of Detoxification and DNA Repair Genes. INTERNATIONAL JOURNAL OF TOXICOLOGY 33:518-522(2014).

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