gsto2
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  • Official Full Name
  • glutathione S-transferase omega 2
  • Background
  • The protein encoded by this gene is an omega class glutathione S-transferase (GST). GSTs are involved in the metabolism of xenobiotics and carcinogens. Four transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • GSTO2; glutathione S-transferase omega 2; glutathione S-transferase omega-2; bA127L20.1; Glutathione S transferase like protein; Glutathione S transferase omega 2; GSTO 2; GSTO-2; GSTO2_HUMAN; glutathione-S-transferase-like protein; bA127L20.1 (novel glutathione-S-transferase)
Cat.#:GSTO2-4426HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GSTO2 Protein, GST-tagged
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Cat.#:GSTO2-1961HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Glutathione S-Transferase Omega 2, His-tagged
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Cat.#:GSTO2-15855HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GSTO2, His-tagged
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Cat.#:GSTO2-1996RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GSTO2 Protein, His-tagged
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Cat.#:GSTO2-1759ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GSTO2
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Cat.#:GSTO2-5710HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human GSTO2 293 Cell Lysate
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Involved Pathway

GSTO2 involved in several pathways and played different roles in them. We selected most pathways GSTO2 participated on our site, such as Biological oxidations, Chemical carcinogenesis, Drug metabolism - cytochrome P450, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSTO2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Biological oxidations
CYP46A1; FDX1L; ACY3; CYP2E1; ACSM1; CYP2K22; ADH7; CYP4F12; CYP3C4; SULT4A1
Chemical carcinogenesis
GSTM1; CYP2E1; GSTO2; ALDH3B2; CHRNA7; CYP3A7; GSTM4; MGST3; UGT1A1; GSTP1
Drug metabolism - cytochrome P450
ADH4; GSTK1; ADH2-2; CYP3A5; CYP2B6; CYP2A6; ADH1A; CYP2D6; CYP2C19; CYP2C8
Glutathione conjugation
GSTO2; GGTLC1; GSTK1; AKR1A1; GGT6
Glutathione metabolism
GPX5; GPX4B; G6PDX; GPX4A; GSTA2; GSTA1; GSTA; GSTA3; MGST1.1; GPX8
Metabolism
MED26; SLC4A1B; ALOX5B.3; CYP3C1; CYP11B1; NHLRC1; FAAH2; CYP2A7; KCNB1; Sult2a6
Metabolism of vitamins and cofactors
NAMPT; CTRC; SLC23A2; SLC46A1; LOC100686744; GSTO2; MMADHC; CBLC-1; SLC25A32A; SLC19A2
Metabolism of water-soluble vitamins and cofactors
KCNG4; SLC2A3; ELA2L; NAMPT; GPHN; SLC52A3; SLC19A2; ELA2; PDZD11; CYB5R3

Protein Function

GSTO2 has several biochemical functions, for example, glutathione dehydrogenase (ascorbate) activity, glutathione transferase activity, methylarsonate reductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GSTO2 itself. We selected most functions GSTO2 had, and list some proteins which have the same functions with GSTO2. You can find most of the proteins on our site.
Function
Related Protein
Function glutathione dehydrogenase (ascorbate) activity
Related Protein GSTO1; GSTO2
Function glutathione transferase activity
Related Protein EEF1G; GSTZ1; GSTA4; GSTM2; GSTT2B; GSTT4; GDAP1; MGST3; GSTA1; GSTP2
Function methylarsonate reductase activity
Related Protein GSTO1; GSTO2
Function oxidoreductase activity
Related Protein HMGCRA; CYP2Y3; CYP4A14; CYP24A1; ALDH9A1A.2; AOX3L1; KDM1B; AKR1A1A; H2-KE6; KDM1A
Function protein binding
Related Protein VANGL1; AGBL1; LINGO1B; GP6; RBM5; C4BP; PARP2; DOT1L; C14orf169; SOCS6

Interacting Protein

GSTO2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSTO2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSTO2.
TFAP2A; MUM1

GSTO2 Related Articles

Glisic, B; Mihaljevic, I; et al. Characterization of glutathione-S-transferases in zebrafish (Danio rerio). AQUATIC TOXICOLOGY 158:50-62(2015).
Azizian-Farsani, F; Rafiei, G; et al. Impact of Sodium Arsenite on Chromosomal Aberrations With Respect to Polymorphisms of Detoxification and DNA Repair Genes. INTERNATIONAL JOURNAL OF TOXICOLOGY 33:518-522(2014).