Recombinant Human Glutathione S-Transferase Omega 2, His-tagged

• Cat.No.: GSTO2-1961H
• Product Overview: Recombinant humanGSTO2 protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: GlutathioneS-transferase omega 2, also known as GSTO2, belongs to the GST superfamilyand may be involved in catalyzing the reaction of glutathione with a widevariety of organic compounds to form thioethers, a process that is essentialfor the metabolism and detoxification of a variety of xenobiotics andcarcinogens. GSTO2 is related to GSTO1 and is expressed in a variety oftissues throughout the body where it functions to catalyze the conversion ofRX and glutathione to HX and R-S-glutathione.
• Form: Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 0.1M NaCl, 40% glycerol.
• Molecular Weight: 30.6 kDa(266aa), confirmed by MALDI-TOF.
• Purity: > 85%by SDS-PAGE
• Concentration: 0.25mg/ml (determined by Bradford assay)
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSMSGDATR TLGKGSQPPG PVPEGLIRIY SMRFCPYSHR TRLVLKAKDIRHEVVNINLR NKPEWYYTKHPFGHIPVLET SQCQLIYESV IACEYLDDAY PGRKLFPYDP YERARQKMLLELFCKVPHLT KECLVALRCG RECTNLKAAL RQEFSNLEEI LEYQNTTFFG GTCISMIDYL LWPWFERLDVYGILDCVSHT PALRLWISAM KWDPTVCALL MDKSIFQGFL NLYFQNNPNA FDFGLC
• Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: GSTO2 glutathioneS-transferase omega 2 [ Homo sapiens ]
• Official Symbol: GSTO2
• Synonyms: GSTO2; glutathione S-transferase omega 2;bA127L20.1; glutathione S-transferase omega-2; GSTO-2;glutathione-S-transferase-like protein; bA127L20.1 (novelglutathione-S-transferase); EC 2.5.1.18; OTTHUMP00000020440;OTTHUMP00000020441
• Gene ID: 119391
• mRNA Refseq: NM_183239
• Protein Refseq: NP_899062
• MIM: 612314
• UniProt ID: Q9H4Y5
• Chromosome Location: 10q25.1
• Pathway: Biological oxidations; Drugmetabolism-cytochrome P450; Glutathione conjugation; Metabolism; Metabolismof vitamins and cofactors; Metabolism of water-soluble vitamins andcofactors; Metabolism of xenobiotics by cytochrome P450; Phase IIconjugation; Vitamin C (ascorbate) metabolism
• Function: glutathione dehydrogenase (ascorbate)activity; glutathione transferase activity; oxidoreductase activity;transferase activity