H2AFJ
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Official Full Name
H2AFJ H2A histone family, member J [ Homo sapiens ] -
Overview
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is located on chromosome 12 and encodes a variant H2A histone. The protein is divergent at the C-terminus compared to the consensus H2A histone family member. -
Synonyms
H2A histone family, member J;14456;Ensembl:ENSG00000246705;MGC921, FLJ10903, FLJ52230;histone H2A.J;H2a/j;H2AJ
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- Avi
- Fc
Involved Pathway
H2AFJ involved in several pathways and played different roles in them. We selected most pathways H2AFJ participated on our site, such as Alcoholism,Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with H2AFJ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Alcoholism | HIST2H4,HIST1H2AE,HIST1H2AG,PPP1CC,HIST2H2BB,CREB3L3,DRD1,GNB1,HIST1H4B,HIST2H4A |
| Systemic lupus erythematosus | H3F3B,HIST1H3A,C2,HIST1H2AF,HLA-DRB3,TRIM21,GM14478,C1QC,HIST1H4F,HIST1H2AJ |
Protein Function
H2AFJ has several biochemical functions, for example, DNA binding,molecular_function,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by H2AFJ itself. We selected most functions H2AFJ had, and list some proteins which have the same functions with H2AFJ. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein heterodimerization activity | VOX,HIST1H4L,NKX2-5,SAE1,GTF2A1,TAF8,HOMER2,MYO5A,AHR,SMAD1 |
| molecular_function | GM13305,GM4179,CRYGM2D12,CLDN5,MUP17,PRF1.6,TNNI1B,SLC45A4,TSPAN9,SFT2D2 |
| DNA binding | NEUROD4,ACD,DR1,DMBX1A,MNX2A,SCMH1,DRL,RB1,TBX3A,MIER1B |
Interacting Protein
H2AFJ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with H2AFJ here. Most of them are supplied by our site. Hope this information will be useful for your research of H2AFJ.
xav939;Smad6;NS;NS;US11;P/V/C;P/V/C;SPI-2;P/V;k7_vaccw;VP35;NS;nsp1_rotp5;P/V/C;polg_hcvco;NS1
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