Recombinant Human H2AFJ Protein, HIS-tagged

• Cat.No.: H2AFJ-120H
• Product Overview: Recombinant Human H2AFJ, transcript variant 1, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is located on chromosome 12 and encodes a replication-independent histone that is a variant H2A histone. The protein is divergent at the C-terminus compared to the consensus H2A histone family member. This gene also encodes an antimicrobial peptide with antibacterial and antifungal activity.
• Source: E. coli
• Species: Human
• Tag: HIS
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 14 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: H2AFJ H2A histone family, member J [ Homo sapiens ]
• Official Symbol: H2AFJ
• Synonyms: H2A histone family, member J; 14456; Ensembl:ENSG00000246705; MGC921, FLJ10903, FLJ52230; histone H2A.J;H2a/j; H2AJ
• Gene ID: 55766
• mRNA Refseq: NM_177925.2
• Protein Refseq: NP_808760.1
• UniProt ID: Q9BTM1