HCCS Protein, holocytochrome c synthase

HCCS

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HCCS

Official Full Name holocytochrome c synthase
Background The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene.
Synonyms HCCS; holocytochrome c synthase; holocytochrome c synthase (cytochrome c heme lyase); cytochrome c-type heme lyase; CCHL; cytochrome c heme lyase; OTTHUMP00000022904; OTTHUMP00000022905; DKFZp779I1858; EC 4.4.1.17; Holocytochrome c type synthase; MCOPS7; OTTHUMP00000022903; OTTMUSP00000021173; OTTMUSP00000021174; RGD1563855; RP23-37L2.1; cytochrome c heme-lyase; holocytochrome c-type synthase
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Hccs-1099M Recombinant Mouse Hccs Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human HCCS-1059H Recombinant Human HCCS Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human HCCS-13691H Recombinant Human HCCS, His-tagged E.coli His
    Human HCCS-4615H Recombinant Human HCCS Protein, GST-tagged Wheat Germ GST
    Human HCCS-773HCL Recombinant Human HCCS cell lysate N/A
    Mouse HCCS-7513M Recombinant Mouse HCCS Protein Mammalian Cell His
    Chicken HCCS-2932C Recombinant Chicken HCCS Mammalian Cell His

    HCCS involved in several pathways and played different roles in them. We selected most pathways HCCS participated on our site, such as Porphyrin and chlorophyll metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with HCCS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Porphyrin and chlorophyll metabolism HMBSA; HCCSB; UGT1A3; GUSB; UGT1A6; UGT1AB; UROD; UGT2B15; UGT2B7; HEPH

    HCCS has several biochemical functions, for example, holocytochrome-c synthase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HCCS itself. We selected most functions HCCS had, and list some proteins which have the same functions with HCCS. You can find most of the proteins on our site.

    Function Related Protein
    holocytochrome-c synthase activity HCCSA.1; HCCSB; HCCS
    metal ion binding C6AST3; UNC13B; TIMM8A2; ZFP36; UQCRC2A; POLR3A; GDPD4; ROCK2; GLIS2B; RRM2B

    HCCS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HCCS here. Most of them are supplied by our site. Hope this information will be useful for your research of HCCS.

    MROH1; CRTC3; TIMMDC1; MRPL17

    Harada, K; Baba, Y; et al. LINE-1 Methylation Level and Patient Prognosis in a Database of 208 Hepatocellular Carcinomas. ANNALS OF SURGICAL ONCOLOGY 22:1280-1287(2015).
    Ei, S; Hibi, T; et al. Cryoablation Provides Superior Local Control of Primary Hepatocellular Carcinomas of > 2 cm Compared with Radiofrequency Ablation and Microwave Coagulation Therapy: An Underestimated Tool in the Toolbox. ANNALS OF SURGICAL ONCOLOGY 22:1294-1300(2015).

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