hif1an
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  • Official Full Name
  • hypoxia inducible factor 1, alpha subunit inhibitor
  • Background
  • Hypoxia-inducible factor 1-alpha inhibitor is a protein that in humans is encoded by the HIF1AN gene.
  • Synonyms
  • HIF1AN; hypoxia inducible factor 1, alpha subunit inhibitor; hypoxia-inducible factor 1-alpha inhibitor; DKFZp762F1811; FIH1; FLJ20615; FLJ22027; Peptide aspartate beta dioxygenase; FIH-1; factor inhibiting HIF1; factor inhibiting HIF-1; peptide-aspartate
Cat.#:HIF1AN-249HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human HIF1AN Protein, MYC/DDK-tagged
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Cat.#:HIF1AN-448HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HIF1AN Protein, His-tagged
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Cat.#:HIF1AN-4748HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HIF1AN Protein, GST-tagged
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Cat.#:HIF1AN-29315THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HIF1AN
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Cat.#:HIF1AN-361HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Hypoxia-Inducible Factor 1, Alpha Subunit Inhibitor
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Cat.#:HIF1AN-5022HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Hypoxia Inducible Factor 1, Alpha Subunit Inhibitor
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Cat.#:HIF1AN-7623MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse HIF1AN Protein
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Cat.#:HIF1AN-11541ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish HIF1AN
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Cat.#:HIF1AN-5564HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human HIF1AN 293 Cell Lysate
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Involved Pathway

HIF1AN involved in several pathways and played different roles in them. We selected most pathways HIF1AN participated on our site, such as Cellular response to hypoxia, Cellular responses to stress, HIF-2-alpha transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIF1AN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cellular response to hypoxia
EGLN2; EGLN1B; EGLN3; HIF1AN; HIF3A; HIF1AL; EPAS1B
Cellular responses to stress
EHMT2; PRDX3; TXN2; ATG9A; EGLN3; Txn1; DPF1; TERF2; RBBP7; C11orf73
HIF-2-alpha transcription factor network
EGLN3; HIF1AN; CITED2; EGLN2
Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
HIF1AN; NAA10; GNB2L1; COPS5; HIF3A
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha
HIF1AN; EPAS1B
Regulation of Hypoxia-inducible Factor (HIF) by oxygen
EGLN1B; HIF3A; EGLN3; EPAS1B; HIF1AN; EGLN2; HIF1AL

Protein Function

HIF1AN has several biochemical functions, for example, NF-kappaB binding, Notch binding, ankyrin repeat binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HIF1AN itself. We selected most functions HIF1AN had, and list some proteins which have the same functions with HIF1AN. You can find most of the proteins on our site.
Function
Related Protein
Function NF-kappaB binding
Related Protein BCL10; NFKBIA; CDKN2A; MTDH; AP1S2; HIF1AN; NPM1; CDK5RAP3; NFKBID; EP300
Function Notch binding
Related Protein JAG1B; JAG2; JAG1A; ADAM17; NCOR2; DTX1; HIF1AN; NOV; AAK1; DLL4
Function ankyrin repeat binding
Related Protein HIF1AN; RELA; SHANK1
Function carboxylic acid binding
Related Protein PCK1; HMGCL; AKR1C21; GRHPR; GOT1; HIF1AN; AKR1C2
Function cofactor binding
Related Protein C3; ME3; HACL1; PGAM2; ASNS; LMO2; PHYH; ACLYA; ACLY; TKT
Function iron ion binding
Related Protein CYP2AD2; TET1; HBB-Y; CYGB2; CYP7A1A; CYP2AA7; AOX4; PPEF1; CYP3C1; CYP2D6
Function oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
Related Protein ALKBH8; C14orf169; P4HTM; PHF8; TYW5; EGLN3; EGLN2; ALKBH5; KDM5BA; EGLN1
Function oxygen sensor activity
Related Protein EGLN2; NOX4; HIF1AN
Function peptidyl-asparagine 3-dioxygenase activity
Related Protein HIF1AN
Function peptidyl-histidine dioxygenase activity
Related Protein HIF1AN
Function protein binding
Related Protein YIPF2; PIP5K1B; POLD2; BABAM1; GOPC; TNFRSF1A; NR2F6; ANTXR1; RNF216; RINT1
Function protein homodimerization activity
Related Protein TOX3; MCL1B; ANXA1; MAPK4; HNF1B; NPR3; TFAP2B; DNTTIP1; TESCA; GRIK1
Function zinc ion binding
Related Protein UBR3; ZNRF4; Shh; CA2; SPRYD5; MARCH1; TRIM63; PYGO1; BFAR; CA3

Interacting Protein

HIF1AN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIF1AN here. Most of them are supplied by our site. Hope this information will be useful for your research of HIF1AN.
ASB9; HIF1A; TNKS2; TNKS; GABPB2; TRPV4; OTUD7B; ASB13; INVS

HIF1AN Related Articles

Liu, Y; Zhang, LW; et al. DNA-PKcs Deficiency Inhibits Glioblastoma Cell-Derived Angiogenesis After Ionizing Radiation. JOURNAL OF CELLULAR PHYSIOLOGY 230:1094-1103(2015).
Shida, T; Nozawa, T; et al. Fluvastatin-induced reduction of oxidative stress ameliorates diabetic cardiomyopathy in association with improving coronary microvasculature. HEART AND VESSELS 29:532-541(2014).