HNRNPC Protein, heterogeneous nuclear ribonucleoprotein C (C1/C2)


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Official Full Name heterogeneous nuclear ribonucleoprotein C (C1/C2)
Background This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.
Synonyms HNRNPC; heterogeneous nuclear ribonucleoprotein C (C1/C2); HNRPC; heterogeneous nuclear ribonucleoproteins C1/C2; hnRNP C1/C2; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2 protein; C1; C2; HNRNP; SNRPC; MGC1
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Hnrnpc-1148M Recombinant Mouse Hnrnpc Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human HNRNPC-13868H Recombinant Human HNRNPC, GST-tagged E.coli GST
    Human HNRNPC-31724TH Recombinant Human HNRNPC, His-tagged E.coli His
    Human HNRNPC-31751TH Recombinant Human HNRNPC, His-tagged E.coli His
    Human HNRNPC-3481H Recombinant Human HNRNPC, His-tagged E.coli His
    Human HNRNPC-4901H Recombinant Human HNRNPC Protein, GST-tagged Wheat Germ GST
    Human HNRNPC-5026H Recombinant Human Heterogeneous Nuclear Ribonucleoprotein C, His-tagged Human His
    Human HNRNPC-5449HCL Recombinant Human HNRNPC 293 Cell Lysate HEK293 N/A
    Mouse HNRNPC-7760M Recombinant Mouse HNRNPC Protein Mammalian Cell His
    Rhesus Macaque HNRNPC-2121R Recombinant Rhesus monkey HNRNPC Protein, His-tagged Mammalian Cell His
    Zebrafish HNRNPC-12308Z Recombinant Zebrafish HNRNPC Mammalian Cell His

    HNRNPC involved in several pathways and played different roles in them. We selected most pathways HNRNPC participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with HNRNPC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Spliceosome MAGOH2; SNRNP70; LSM4; U2SURP; PRPF19; HSPA6; TCERG1A; PRPF6; PRPF38A; SRSF10

    HNRNPC has several biochemical functions, for example, N6-methyladenosine-containing RNA binding, RNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HNRNPC itself. We selected most functions HNRNPC had, and list some proteins which have the same functions with HNRNPC. You can find most of the proteins on our site.

    Function Related Protein
    N6-methyladenosine-containing RNA binding YTHDF2; YTHDC1; YTHDF3; HNRNPC; YTHDF1
    RNA polymerase II core promoter proximal region sequence-specific DNA binding NEUROD1; PLAG1; ZNF253; FOSB; JUNB; ELF4; ZNF680; GCFC2; MTF1; SREBF1
    RNA polymerase II distal enhancer sequence-specific DNA binding SFPI1; NFATC1; SIX3; T; GZF1; BACH1A; ATF2; NFE2L1; SOX10; HOXB5
    identical protein binding BLOC1S6; DVL2; SQSTM1; FUS; UBE2G2; APLP1; PAK2; GOT2A; MTPAP; COL18A1
    mRNA 3-UTR binding ELAVL1; PUM1; IGF2BP1; CRYZ; RBM24; PUM2; LARP1; KHSRP; CPEB2; FXR1
    nucleosomal DNA binding NSBP1; HMGN2; RCC1; HMGN5; HMGN1; H2AFY; HMGN3; H2AFZ; HMGA2; H1FOO
    nucleotide binding RHOT1A; PTBP2B; ATP1A1B; RERGLA; PSMC1B; PTK6B; FHIT; TUBA2; CDC34B; ABT1
    poly(A) RNA binding CDK5R2; UPF1; FAM98A; DDX21; SEC23IP; RPL22; TRNAU1AP; CHERP; MRTO4; EIF1B
    poly(U) RNA binding PATL1; HNRNPH1; KHDRBS1; MSI1; DIS3L2; PABPC4; MSI2; RBM11; PABPC1; PNPT1
    protein binding RABL2A; FOSL2; SENP6; TMX3; MRPS27; MPDZ; ETL4; RANBP6; HPSE; GATA3
    telomerase RNA binding PINX1; DKC1; TERT; WRAP53; HNRNPU; HNRNPC; NHP2; GAR1; NOP10

    HNRNPC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HNRNPC here. Most of them are supplied by our site. Hope this information will be useful for your research of HNRNPC.


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