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HNRNPC

  • Official Full Name

    heterogeneous nuclear ribonucleoprotein C (C1/C2)

  • Overview

    This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.
  • Synonyms

    HNRNPC; heterogeneous nuclear ribonucleoprotein C (C1/C2); HNRPC; heterogeneous nuclear ribonucleoproteins C1/C2; hnRNP C1/C2; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2 protein; C1; C2; HNRNP; SNRPC; MGC1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • MYC
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HNRNPC-13868H Recombinant Human HNRNPC, GST-tagged E.coli GST 1-293a.a.
Human HNRNPC-31724TH Recombinant Human HNRNPC, His-tagged E.coli His 293 amino acids
Human HNRNPC-5026H Recombinant Human Heterogeneous Nuclear Ribonucleoprotein C, His-tagged Human His
Human HNRNPC-4901H Recombinant Human HNRNPC Protein, GST-tagged Wheat Germ GST
Human HNRNPC-3481H Recombinant Human HNRNPC, His-tagged E.coli His
Human HNRNPC-31751TH Recombinant Human HNRNPC, His-tagged E.coli His
Human HNRNPC-5449HCL Recombinant Human HNRNPC 293 Cell Lysate HEK293 N/A
Human HNRNPC-1085H Recombinant Human HNRNPC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HNRNPC-1085H-B Recombinant Human HNRNPC Protein Pre-coupled Magnetic Beads HEK293
Human HNRNPC-3679HF Recombinant Full Length Human HNRNPC Protein, GST-tagged In Vitro Cell Free System GST 250 amino acids
Human HNRNPC-562HFL Recombinant Full Length Human HNRNPC Protein, C-Flag-tagged Mammalian cells Flag
Mouse HNRNPC-7760M Recombinant Mouse HNRNPC Protein Mammalian Cell His
Mouse HNRNPC-4259M Recombinant Mouse HNRNPC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Hnrnpc-1148M Recombinant Mouse Hnrnpc Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse HNRNPC-4259M-B Recombinant Mouse HNRNPC Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque HNRNPC-2121R Recombinant Rhesus monkey HNRNPC Protein, His-tagged Mammalian Cell His
Rhesus Macaque HNRNPC-1942R-B Recombinant Rhesus Macaque HNRNPC Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque HNRNPC-1942R Recombinant Rhesus Macaque HNRNPC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish HNRNPC-12308Z Recombinant Zebrafish HNRNPC Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HNRNPC involved in several pathways and played different roles in them. We selected most pathways HNRNPC participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with HNRNPC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
SpliceosomeSNRPA;U2AF1;DDX5;EFTUD2;SRSF5;HSPA1A;NHP2L1B;SNRPD2;HNRPKL

HNRNPC has several biochemical functions, for example, N6-methyladenosine-containing RNA binding, RNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HNRNPC itself. We selected most functions HNRNPC had, and list some proteins which have the same functions with HNRNPC. You can find most of the proteins on our site.

Function Related Protein
N6-methyladenosine-containing RNA bindingYTHDC1;YTHDF1;YTHDF3;YTHDF2;HNRNPC
RNA bindingSRSF3;ENDOU2;IFIT8;SRSF1;RBM6;DUSP11;OOEP;EXOSC7;RNASET2
RNA polymerase II core promoter proximal region sequence-specific DNA bindingTFAP4;EN1;HOXA10;ZNF331;SMAD3;HHEX;RFX4;MIXL1;ZNF502
RNA polymerase II distal enhancer sequence-specific DNA bindingH3F3A;GATA2;REL;JUN;H3F3B;POU4F1;ZBTB16;MIXL1;BACH1A
identical protein bindingRNF4;FHL2;NCL;SSNA1;ALS2CL;PIP4K2C;PLEKHH2;DYNLT1F;VWA2
mRNA 3-UTR bindingRBM38;CPEB1;RNPS1;FXR1;IGF2BP2;TUT1;PUM1;RBMS3;HNRNPC
nucleosomal DNA bindingH3F3A;HMGN2;H1FOO;HNRNPC;HMGN4;HMGN3;H2AFZ;HMGN5;RCC1
nucleotide bindingORC4;NONO;CSNK1G2A;KIF15;RASEF;CAMKK1B;EEF2A.2;ARF3A;SMOK2B
poly(A) RNA bindingJUN;RBM3;HIST2H4A;DHX37;DQX1;COA6;RARS2;THUMPD1;RBMX2
poly(U) RNA bindingMSI1;PATL2;PABPC1;HNRNPC;KHDRBS2;KHDRBS1;MSI2;PABPC4;RBM11
protein bindingCCDC24;RHOT2;DIAP1;DOCK9;WDR4;MYB;RING1;KRTAP9-2;BCAM
telomerase RNA bindingDKC1;GAR1;PINX1;WRAP53;TERT;NOP10;HNRNPC;NHP2;HNRNPU

HNRNPC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HNRNPC here. Most of them are supplied by our site. Hope this information will be useful for your research of HNRNPC.

RALYL; KPNA3; RBM41

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