hnrnpc
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  • Official Full Name
  • heterogeneous nuclear ribonucleoprotein C (C1/C2)
  • Background
  • This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.
  • Synonyms
  • HNRNPC; heterogeneous nuclear ribonucleoprotein C (C1/C2); HNRPC; heterogeneous nuclear ribonucleoproteins C1/C2; hnRNP C1/C2; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2 protein; C1; C2; HNRNP; SNRPC; MGC1
Cat.#:HNRNPC-4901HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HNRNPC Protein, GST-tagged
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Cat.#:HNRNPC-13868HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HNRNPC, GST-tagged
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Cat.#:HNRNPC-31724THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HNRNPC, His-tagged
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Cat.#:HNRNPC-31751THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HNRNPC, His-tagged
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Cat.#:HNRNPC-3481HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HNRNPC, His-tagged
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Cat.#:HNRNPC-5026HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Heterogeneous Nuclear Ribonucleoprotein C, His-tagged
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Cat.#:HNRNPC-7760MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse HNRNPC Protein
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Cat.#:HNRNPC-2121RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey HNRNPC Protein, His-tagged
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Cat.#:HNRNPC-12308ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish HNRNPC
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Cat.#:HNRNPC-5449HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human HNRNPC 293 Cell Lysate
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Involved Pathway

HNRNPC involved in several pathways and played different roles in them. We selected most pathways HNRNPC participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with HNRNPC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Spliceosome
HNRNPU; THOC3; HNRPK; MAGOH2; CDC40; PHF5A; TTC6; U2AF2B; SF3A1; MAGOH

Protein Function

HNRNPC has several biochemical functions, for example, N6-methyladenosine-containing RNA binding, RNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HNRNPC itself. We selected most functions HNRNPC had, and list some proteins which have the same functions with HNRNPC. You can find most of the proteins on our site.
Function
Related Protein
Function N6-methyladenosine-containing RNA binding
Related Protein YTHDC1; HNRNPC; YTHDF2; YTHDF3; YTHDF1
Function RNA binding
Related Protein RNMT; THOC1; PATL1; DAZ4; HNRNPL2; HNRNPH3; RPL15; EIF2S2; PDCD11; DDX3Y
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein SMAD2; RBPJA; CUX2; TCF7L2; CDX4; ETV6; MYBL1; OTX2; ZNF502; OTX1
Function RNA polymerase II distal enhancer sequence-specific DNA binding
Related Protein BACH1; GZF1; SFPQ; HNRNPC; PBX3; PAX4; MIXL1; REL; ARID3B; BACH2
Function identical protein binding
Related Protein CLDN20; AGXT2; CD74; TPRGL; LECT2; SHARPIN; DRD2; LEPR; S100A1; B2M
Function mRNA 3-UTR binding
Related Protein PARN; PPP1R2P9; SECISBP2; HNRNPC; CPEB4; YBX2; CRYZ; CPEB1B; CIRBP; PUM2
Function nucleosomal DNA binding
Related Protein NSBP1; HMGN4; H1FOO; H3F3A; RCC1; H3F3B; HMGN1; HMGN3; HMGN5; HMGA2
Function nucleotide binding
Related Protein RBM24; TLK1B; PABPC5; HNRNPAB; DCLK3; BMPR1AA; ARL4CA; MYO7A; SMYHC3; NMRK2
Function poly(A) RNA binding
Related Protein BRIX1; GPATCH8; RBM34; DDX31; PTBP1; HMGB2; PPHLN1; FKBP4; PPP1R10; HIST2H4A
Function poly(U) RNA binding
Related Protein PABPC4; MSI1; KHDRBS2; RBM11; MSI2; PATL1; PABPC1; DIS3L2; PATL2; HNRNPH1
Function protein binding
Related Protein MED28; SNX1; KCNE2; GET4; ZNF524; CSPP1; COG8; TMEM203; ABLIM3; ALDOB
Function telomerase RNA binding
Related Protein PINX1; TERT; GAR1; DKC1; WRAP53; HNRNPC; NHP2; NOP10; HNRNPU

Interacting Protein

HNRNPC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HNRNPC here. Most of them are supplied by our site. Hope this information will be useful for your research of HNRNPC.
RALYL; KPNA3; RBM41