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HSD17B11

  • Official Full Name

    hydroxysteroid (17-beta) dehydrogenase 11

  • Overview

    Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001;(PubMed 11165019)).
  • Synonyms

    HSD17B11; hydroxysteroid (17-beta) dehydrogenase 11; dehydrogenase/reductase (SDR family) member 8 , DHRS8; estradiol 17-beta-dehydrogenase 11; 17 BETA HSD11; 17 BETA HSDXI; PAN1B; retinal short chain dehydrogenase/reductase 2; RetSDR2; SDR16C2; short cha;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HSD17B11-28398TH Recombinant Human HSD17B11, His-tagged E.coli His 266 amino acids
Human HSD17B11-5066H Recombinant Human HSD17B11 Protein, GST-tagged Wheat Germ GST
Human HSD17B11-13955H Recombinant Human HSD17B11, His-tagged E.coli His 15-300a.a.
Human HSD17B11-943H Recombinant Human HSD17B11, 20-285 aa, His-tagged E.coli His
Human HSD17B11-473HCL Recombinant Human HSD17B11 cell lysate N/A
Human HSD17B11-4694H Recombinant Human HSD17B11 protein, His-SUMO-tagged E.coli His-SUMO 20-300aa
Human HSD17B11-2131H Recombinant Human HSD17B11 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human HSD17B11-53HFL Recombinant Full Length Human HSD17B11 Protein, C-Flag-tagged Mammalian cells Flag
Human HSD17B11-3548H Recombinant Human HSD17B11 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HSD17B11-1102H Recombinant Human HSD17B11 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HSD17B11-3842HF Recombinant Full Length Human HSD17B11 Protein, GST-tagged In Vitro Cell Free System GST 300 amino acids
Human HSD17B11-1102H-B Recombinant Human HSD17B11 Protein Pre-coupled Magnetic Beads HEK293
Mouse Hsd17b11-524M Recombinant Mouse Hsd17b11 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat HSD17B11-2923R Recombinant Rat HSD17B11 Protein Mammalian Cell His
Rat HSD17B11-2578R Recombinant Rat HSD17B11 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HSD17B11-2578R-B Recombinant Rat HSD17B11 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey HSD17B11-598C Recombinant Cynomolgus HSD17B11 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey HSD17B11-344C-B Recombinant Cynomolgus Monkey HSD17B11 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey HSD17B11-344C Recombinant Cynomolgus Monkey HSD17B11 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HSD17B11-2154R Recombinant Rhesus monkey HSD17B11 Protein, His-tagged Mammalian Cell His
Rhesus Macaque HSD17B11-1975R Recombinant Rhesus Macaque HSD17B11 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HSD17B11-1975R-B Recombinant Rhesus Macaque HSD17B11 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HSD17B11 Related Articles

HSD17B11 involved in several pathways and played different roles in them. We selected most pathways HSD17B11 participated on our site, such as Estrogen biosynthesis, Metabolism, Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSD17B11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Estrogen biosynthesisHSD17B11;CYP19A1;AKR1B15
MetabolismPTGDSA;AADAC;DBH;GRX2;ACSF2;G0S2;LOC100686744;STARD5;CYP2A13
Metabolism of lipids and lipoproteinsACOT6;FAAH2B;CYP8B2;TPTE;Alb;CTGF;CYP4B1;ACOT12;ACER1
Metabolism of steroid hormones and vitamin DAKR1B15;GC;PPP1R2;CYP27B1;HSD17B11;CYP24A1;CYP2R1;STARD5
estradiol biosynthesis I
superpathway of steroid hormone biosynthesis

HSD17B11 has several biochemical functions, for example, estradiol 17-beta-dehydrogenase activity, steroid dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HSD17B11 itself. We selected most functions HSD17B11 had, and list some proteins which have the same functions with HSD17B11. You can find most of the proteins on our site.

Function Related Protein
estradiol 17-beta-dehydrogenase activityHSD17B14;HSD17B12A;HSD17B12B;RDH8;AKR1B15;RDH8B;AKR1C6;HSD17B2;H2-KE6
steroid dehydrogenase activityH2-KE6;HSD3B6;HSD11B1LA;HSD3B5;AKR1C21;AKR1C6;SDR42E1;SDR16C6;HSD17B11

HSD17B11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSD17B11 here. Most of them are supplied by our site. Hope this information will be useful for your research of HSD17B11.

PTP4A3; BRF2; GSTK1

Legeza, B; Balazs, Z; et al. The Microsomal Enzyme 17 beta-Hydroxysteroid Dehydrogenase 3 Faces the Cytoplasm and Uses NADPH Generated by Glucose-6-Phosphate Dehydrogenase. ENDOCRINOLOGY 154:205-213(2013).
Patel, K; Farlow, EC; et al. Enhancement of a multianalyte serum biomarker panel to identify lymph node metastases in non-small cell lung cancer with circulating autoantibody biomarkers. INTERNATIONAL JOURNAL OF CANCER 129:133-142(2011).
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