ifnar2
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  • Official Full Name
  • interferon (alpha and beta) receptor 2
  • Background
  • This antibody was produced by In vivo genetic immunization of IFNAR1 knockout mice with a plasmid encoding the extracellular domain of murine IFNAR1. IFNAR1 and IFNAR2 are coexpressed on nearly all cells and make up the heterodimeric receptor that binds a
  • Synonyms
  • IFNAR2; interferon (alpha and beta) receptor 2; interferon alpha/beta receptor 2; IFN-R-2; interferon receptor 2c; IFN-alpha/beta receptor 2; type I interferon receptor 2; interferon-alpha/beta receptor 2; type I interferon alpha/beta receptor 2a; Ifnar-2
Cat.#:IFNAR2-2339MTag:His
Source (Host):YeastSpecies:Mouse
Product nameRecombinant Mouse IFNAR2 Protein (22-242 aa), His-tagged
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Cat.#:IFNAR2-1152HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IFNAR2 protein, His & T7-tagged
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Cat.#:IFNAR2-14078HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IFNAR2, GST-tagged
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Cat.#:IFNAR2-156HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNAR2, His-tagged
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Cat.#:IFNAR2-157HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNAR2, Fc-tagged
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Cat.#:IFNAR2-214HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNAR2 Protein, Fc-tagged
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Cat.#:IFNAR2-25HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNAR2, Fc Chimera
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Cat.#:IFNAR2-27987THTag:His
Source (Host):Species:Human
Product nameRecombinant Human IFNAR2, His-tagged
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Cat.#:IFNAR2-3349HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNAR2, His tagged
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Cat.#:IFNAR2-6952HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human Interferon(alpha, beta and omega) Receptor 2, Fc-tagged
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Cat.#:Ifnar2-683MTag:Fc Chimera
Source (Host):NSO cellsSpecies:Mouse
Product nameRecombinant Mouse Ifnar2, Fc Chimera
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Cat.#:IFNAR2-8038MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse IFNAR2 Protein
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Cat.#:IFNAR2-1194CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IFNAR2 Protein, His-tagged
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Cat.#:IFNAR2-6421CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken IFNAR2
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Cat.#:IFNAR2-2243HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNAR2 cell lysate
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Involved Pathway

IFNAR2 involved in several pathways and played different roles in them. We selected most pathways IFNAR2 participated on our site, such as Cytokine-cytokine receptor interaction, PIK-Akt signaling pathway, Osteoclast differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNAR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
CRFB16; CX3CR1; IL13RA1; PRLR; PDGFC; CCL25; IFNPHI1; CCL18; CCL27; CCL3
PIK-Akt signaling pathway
IFNA8; PKN3; KITLG; THBS2; IFNA7; VEGFA; LAMA2; FIGF; NOS3; FGF9
Osteoclast differentiation
FHL2; IKBKB; SOCS3; MAPK3; IFNAR2; NOX3; CYBA; CSF1; FOS; PPP3R1
Toll-like receptor signaling pathway
MAP3K7; MAP2K3; NFKBIA; IRAK4; PIK3R3B; TLR1LA; TLR3; TMED7-TICAM2; IKBKB; Ifna11
Jak-STAT signaling pathway
IL13RA1; Gh; STAT5A; CRFB16; BCL2A; RAF1A; SOCS1; PIK3R3A; IL9R; JAK2B
Natural killer cell mediated cytotoxicity
IFNAR1; IFNA8; CD247; MAPK3; BID; ITGAL; GM-CSF; PPP3CA; IFNGR1; PIK3CA
Hepatitis C
OAS1; MAPK3; CLDN3; CLDN16; STAT2; CLDN6; CD81; PIK3CD; CLDN15; PIK3CA
Measles
IFNA2; OAS3; PIK3R1; RAB9B; Ifna11; TNFSF10; TLR9; BBC3; IFNA5; TP73
Influenza A
MAP2K2; MAP2K3; MAPK9; HSPA1A; IL12A; PIK3CG; TMPRSS2; BLB2; IKBKB; OAS3
Herpes simplex infection
TNFRSF1A; HLA-DQA2; IFNA6; IFNA5; TAP1; LTA; TRAF5; SRPK1A; IFNB; IRF7

Protein Function

IFNAR2 has several biochemical functions, for example, protein binding, protein kinase binding, type I interferon binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFNAR2 itself. We selected most functions IFNAR2 had, and list some proteins which have the same functions with IFNAR2. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein ZIC3; TIMM23; TRIM55; IFI16; UBASH3B; MSH5; FAM162A; NTS; KREMEN1; FLOT2
Function protein kinase binding
Related Protein SREBF1; PRKAB1; SOCS1; TBC1D14; CHEK2; TRIM22; ADRA2A; MAP3K12; KIF14; CEP68
Function type I interferon binding
Related Protein IFNAR2
Function type I interferon receptor activity
Related Protein IFNAR2; IFNAR1

Interacting Protein

IFNAR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFNAR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFNAR2.
IRF9; JAK1; GNB2L1; CREBBP; STAT2; IFNA2

IFNAR2 Related Articles

Ovsyannikova, IG; Salk, HM; et al. Single-nucleotide polymorphism associations in common with immune responses to measles and rubella vaccines. IMMUNOGENETICS 66:663-669(2014).
Kuruganti, S; Accavitti-Loper, MA; et al. Production and characterization of thirteen human type-I interferon-alpha Mark subtypes. PROTEIN EXPRESSION AND PURIFICATION 103:75-83(2014).

IFNAR2 Related Gene Family

Cytokines