IGFBP1
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Official Full Name
Insulin-like Growth Factor Binding Protein 1
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Overview
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. -
Synonyms
AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1; IGFBP1; insulin-like growth factor-binding protein 1; IBP-1; IGFBP-1; OTTHUMP00000159561; OTTHUMP00000207990; OTTHUMP00000214348; binding protein-25; binding protein-26; binding protein-28; placental protein 12; IGF-binding protein 1; amniotic fluid binding protein; growth hormone independent-binding protein; alpha-pregnancy-associated endometrial globulin;
- Recombinant Proteins
- Native Proteins
- Protein Pre-coupled Magnetic Beads
- Cell & Tissue Lysates
- Canine
- Cattle
- Chicken
- Cynomolgus Monkey
- Human
- Mouse
- Pig
- Rat
- Rhesus macaque
- Rhesus Macaque
- E.coli
- HEK293
- HEK293 cells
- HEK293F
- HEK293T
- Human
- Human Cell
- Mammalian Cell
- Mammalian cells
- Mouse Erythrocytes
- Yeast
- C
- His
- His (Fc)
- Avi
- His(C
- ter)
- His|GST
- His|SUMO
- His|T7
- SUMO
- MYC
- DDK
- Myc|DDK
- N/A
- N
- Q&As
- Reviews
Q&As (7)
Ask a questionIGFBP1 influences the progression of certain cancers, particularly those sensitive to hormonal regulation.
Changes in IGFBP1 expression contribute to the aging process and the development of age-related diseases.
IGFBP1 is important for fetal growth and development, regulating growth factor activity during pregnancy.
IGFBP1 affects muscle growth and regeneration, playing a role in conditions involving muscle wasting.
IGFBP1 impacts cardiovascular health, influencing factors like blood vessel growth and atherosclerosis development.
IGFBP1 plays a crucial role in glucose metabolism and insulin sensitivity, impacting overall metabolic health.
IGFBP1 modulates the availability and activity of IGFs, affecting growth and metabolic functions in various tissues.
Customer Reviews (3)
Write a reviewPrecise antibody validation, enhances immunoprecipitation studies.
Efficient protein purification, delivers high yield and purity.
Dependable expertise in protein engineering, unmatched quality.
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