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IL4I1

  • Official Full Name

    interleukin 4 induced 1

  • Overview

    This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
  • Synonyms

    IL4I1; interleukin 4 induced 1; LAO; FIG1; LAAO; L-amino-acid oxidase; Fig-1 protein; IL4-induced protein 1; interleukin four induced 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • CHO
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL4I1-654H Active Recombinant Human Interleukin 4 Induced 1, His-tagged CHO His
Human IL4I1-5225HCL Recombinant Human IL4I1 293 Cell Lysate HEK293 N/A
Human IL4I1-2320H Recombinant Human IL4I1 Protein, His-tagged E.coli N-His Met1-Glu245
Human IL4I1-1817H Recombinant Human IL4I1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IL4I1-01H Active Recombinant Human IL4I1 Protein, His-Tagged Insect Cell His 555aa
Human IL4I1-2613H Recombinant Human IL4I1 protein, His-tagged E.coli His 241-589 aa
Human IL4I1-1178H-B Recombinant Human IL4I1 Protein Pre-coupled Magnetic Beads HEK293
Human IL4I1-1563HFL Recombinant Full Length Human IL4I1 Protein, C-Flag-tagged Mammalian cells Flag
Human IL4I1-1178H Recombinant Human IL4I1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Il4i1-653M Active Recombinant Mouse Interleukin 4 Induced 1, His-tagged CHO His
Mouse Il4i1-639M Active Recombinant Mouse Il4i1 protein, His-tagged CHO His
Mouse IL4I1-8173M Recombinant Mouse IL4I1 Protein Mammalian Cell His
Mouse IL4I1-4518M Recombinant Mouse IL4I1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse IL4I1-4518M-B Recombinant Mouse IL4I1 Protein Pre-coupled Magnetic Beads HEK293
Chicken IL4I1-3716C Recombinant Chicken IL4I1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IL4I1 Related Articles

IL4I1 involved in several pathways and played different roles in them. We selected most pathways IL4I1 participated on our site, such as Alanine, aspartate and glutamate metabolism, Cysteine and methionine metabolism, Valine, leucine and isoleucine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL4I1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Alanine, aspartate and glutamate metabolismALDH5A1;GPT2;ybaS;GOT2A;GOT2B;GFPT2;ADSSL1;RIMKLA;AGXT
Cysteine and methionine metabolismMDH1;LDHA;MAT1A;CBS;MTAP;AHCYL2;GCLM;TAT;MAT2AB
Valine, leucine and isoleucine degradationHMGCS1;ACAA1;HMGCS2;HIBADHB;BCKDHB;IVD;MUT;HIBADH;ACAT2
Tyrosine metabolismAOC2;AOC3;ALDH3A1;HPDA;ADH2-1;ALDH3B2;ALDH1A3;DBH;DCT
Phenylalanine metabolismMAOB;KEG1;GOT2B;AOC3;HPDA;ALDH3B1;ALDH3B2;AOC2;MAOA
Tryptophan metabolismANI_1_2390104;ALDH7A1;AOX4;MAOB;ACAT2;TPH1A;OGDHA;AOX2P;ALDH3A2A
Phenylalanine, tyrosine and tryptophan biosynthesisIL4I1;PAH;GOT2A;TAT;GOT2B;GOT2;GOT1
Metabolic pathwaysPIGW;DLDH;TBXAS1;CHIA.3;MAN1B1;GNPDA2;IDO2;ACSL5;CES1

IL4I1 has several biochemical functions, for example, L-amino-acid oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL4I1 itself. We selected most functions IL4I1 had, and list some proteins which have the same functions with IL4I1. You can find most of the proteins on our site.

Function Related Protein
L-amino-acid oxidase activity

IL4I1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL4I1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL4I1.

Park, JH; Joo, CK; et al. Comparative Study of Tacrolimus and Bevacizumab on Corneal Neovascularization in Rabbits. CORNEA 34:449-455(2015).
Lee, CH; Chang, JSM; et al. IL-1 beta Promotes Malignant Transformation and Tumor Aggressiveness in Oral Cancer. JOURNAL OF CELLULAR PHYSIOLOGY 230:875-884(2015).
  • Q&As
  • Reviews

Q&As (6)

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How to determine the dose of IL4I1 in clinical treatment? 12/12/2022

The dose of IL4I1 in clinical treatment requires a number of preliminary studies, and is determined according to the type and severity of the patient's disease.

What are the biological functions of IL4I1? 02/04/2022

This is mainly involved in the regulation of immune response and anti-tumor effect, and has biological functions such as inhibiting T cell activation and proliferation, inducing macrophage M2 polarization, regulating T cell differentiation and apoptosis.

What problems should be paid attention to when IL4I1 is used in preclinical animal test studies? 01/09/2022

IL4I1 used in preclinical animal experimental studies needs to pay attention to its dose, administration route, administration time and other issues.

Is there any side effect of IL4I1? 01/29/2021

The application of IL4I1 may cause some side effects, such as fever, headache, fatigue, nausea, etc., but its toxic side effects are relatively small.

What is the mechanism of IL4I1 in tumor therapy? 12/30/2020

IL4I1 can inhibit the growth and spread of tumor cells, and at the same time activate immune cells in the body to enhance the body's immune monitoring ability to tumor, so as to achieve the effect of tumor treatment.

How the purification technologies of IL4I1? 06/04/2019

The purification technology of IL4I1 mainly includes affinity chromatography, ion exchange chromatography, gel filtration chromatography and so on.

Customer Reviews (3)

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Reviews
07/19/2022

    The consistency and reliability of this protein are good.

    02/13/2021

      Under the influence of temperature, humidity and light, this protein is stable and durable.

      10/24/2020

        This protein is immunogenic and allergenic, which is even more important for proteins used in drug development.

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