• Official Full Name
  • IQ motif containing GTPase activating protein 2
  • Background
  • IQGAPs are scaffolding proteins involved in mediating cytoskeletal function. They contain multiple protein interaction domains and bind to a growing number of molecules including actin, myosin light chain, calmodulin, E-cadherin, and beta-catenin. Through
  • Synonyms
  • IQGAP2; IQ motif containing GTPase activating protein 2; ras GTPase-activating-like protein IQGAP2
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human IQGAP2 protein, GST-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken IQGAP2
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish IQGAP2

Involved Pathway

IQGAP2 involved in several pathways and played different roles in them. We selected most pathways IQGAP2 participated on our site, such as Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with IQGAP2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Regulation of actin cytoskeleton
RAC1A; Itga10&Itgb1; FGF12; FGD1; MSN; PAK6B; CDC42L; CHRM5A; RHOAC; PIP5K1B

IQGAP2 Related Articles

Tseng, PC; Chen, CL; et al. An increase in integrin-linked kinase non-canonically confers NF-kappa B-mediated growth advantages to gastric cancer cells by activating ERK1/2. CELL COMMUNICATION AND SIGNALING 12:-(2014).
Ma, YY; Jin, ZX; et al. Quercetin suppresses the proliferation of multiple myeloma cells by down-regulating IQ motif-containing GTPase activating protein 1 expression and extracellular signal-regulated kinase activation. LEUKEMIA & LYMPHOMA 55:2597-2604(2014).