Human IQGAP2 Knockdown Cell Lysate

• Cat.No.: IQGAP2-007HKCL
• Product Overview: WB-validated IQGAP2 Knockdown 293T Cell Lysate

Specification

• Species: Human
• Source: 293T
• Tag: Non
• Description: This gene encodes a member of the IQGAP family. The encoded protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. This protein interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Alternative splicing results in multiple transcript variants.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 181 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type 293T cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT 293T cell lysate 1 vial of 100 μg IQGAP2 KD 293T cell lysate
• Protein Families: Druggable Genome
• Protein Pathways: Regulation of actin cytoskeleton
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: IQGAP2 IQ motif containing GTPase activating protein 2 [ Homo sapiens (human) ]
• Official Symbol: IQGAP2
• Synonyms: IQGAP2; IQ motif containing GTPase activating protein 2; ras GTPase-activating-like protein IQGAP2
• Gene ID: 10788
• mRNA Refseq: NM_006633
• Protein Refseq: NP_006624
• MIM: 605401
• UniProt ID: Q13576