kat5
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  • Official Full Name
  • K(lysine) acetyltransferase 5
  • Background
  • The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
  • Synonyms
  • KAT5; K(lysine) acetyltransferase 5; TIP; ESA1; PLIP; TIP60; cPLA2; HTATIP; ZC2HC5; HTATIP1; histone acetyltransferase KAT5; K-acetyltransferase 5; cPLA2 interacting protein; cPLA(2)-interacting protein; 60 kDa Tat-interactive protein; Tat interacting protein, 60kDa; histone acetyltransferase HTATIP; HIV-1 Tat interactive protein, 60kDa;
Cat.#:KAT5-1302HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KAT5 Protein (3-513 aa), His-tagged
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Cat.#:KAT5-5258HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human KAT5 Protein, GST-tagged
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Cat.#:KAT5-1599HTag:GST
Source (Host):Sf 10 Insect cellsSpecies:Human
Product nameRecombinant Human K(lysine) Acetyltransferase 5, GST-tagged
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Cat.#:KAT5-28679THTag:N/A
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human KAT5
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Cat.#:KAT5-5132HTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human K(Lysine) Acetyltransferase 5
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Cat.#:KAT5-518HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human KAT5, His-tagged
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Cat.#:KAT5-8452MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse KAT5 Protein
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Cat.#:KAT5-3155RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat KAT5 Protein
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Cat.#:KAT5-1350HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human KAT5 (Active), GST-tagged
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Cat.#:KAT5-5088HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human KAT5 293 Cell Lysate
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Cat.#:KAT5-5089HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human KAT5 293 Cell Lysate
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Involved Pathway

KAT5 involved in several pathways and played different roles in them. We selected most pathways KAT5 participated on our site, such as ATF-2 transcription factor network, Androgen receptor signaling pathway, C-MYC pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with KAT5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
ATF-2 transcription factor network
RUVBL2; JUNB; JUN; ATF2; DUSP5; KAT5; HRK; CREB1; JUND; DUSP1
Androgen receptor signaling pathway
KAT5; CCDC102A; HMGB2A; CREBBP; ZMIZ1; RNF4; RNF14; PATZ1; SMARCE1; RANBP9
C-MYC pathway
ACTL6A; KAT5; RUVBL2; MYC; HBP1
Cell Cycle
YWHAQ; NUP50; PRKDC; SYCE1; NCAPD3; MYCA; VRK1; CNEP1R1; POLD3; CCNA2
Cell Cycle Checkpoints
RAD9; HUS1; MCM8; THRSP; RNF168; UIMC1; CHEK1; RAD1; CDKN1B; UBE2V2
Cellular Senescence
CBX4; RBBP4; POT1; H3F3D; PHC1; LMNB1; EP400; RNF2; KDM6B; CEBPB
Cellular responses to stress
HSPA14; ATG9A; ATG4A; ACD; SCMH1; H1F0; HSBP1; CDKN2D; MOV10; KAT5
Chromatin modifying enzymes
ING5B; PBRM1; KDM5C; RBBP4; TADA2B; KDM5BA; KANSL3; KAT7A; SMYD2; PHF21A

Protein Function

KAT5 has several biochemical functions, for example, acetyltransferase activity, androgen receptor binding, histone acetyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KAT5 itself. We selected most functions KAT5 had, and list some proteins which have the same functions with KAT5. You can find most of the proteins on our site.
Function
Related Protein
Function acetyltransferase activity
Related Protein CREBBP; HHAT; KAT6B; CML2; Nat3; LPCAT3; KAT2B; AANAT2; NAT14; AANAT1
Function androgen receptor binding
Related Protein PKN1; RAN; TRIM68; PARK7; TGFB1I1; PRPF6; FHL2; FOXH1; KAT5; RNF14
Function histone acetyltransferase activity
Related Protein HAT1; CREBBP; KAT7; KAT7B; NCOA1; KAT6A; KAT8; MED24; KAT2B; ATF2
Function contributes_to histone acetyltransferase activity
Related Protein TAF6L; ELP4; TADA3; TAF5L; SAP130; TADA1; ING3; SUPT3H; TEX30; TADA2B
Function metal ion binding
Related Protein TESK2; ZYMND12; ZFP36L1B; ZNF143; Gh; SP1; EIF2S2; ARG2; ENDOU2; CHSY3
Function protein binding
Related Protein LIN7A; ZG16; ZMAT2; OAS1B; Raet1c; MAP6; CD200R2; VPS4B; ZKSCAN4; SH2D3A
Function repressing transcription factor binding
Related Protein NFYB; GMNN; SKI; TLE4; HDAC4; EIF4E; CTBP1; SRI; PARK7; RUNX2
Function transcription coactivator activity
Related Protein MAX; HINFP; MNT; NCOA3; SMARCA4; UTF1; RUNX1; VGLL1; TADA3; BRCA1

Interacting Protein

KAT5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KAT5 here. Most of them are supplied by our site. Hope this information will be useful for your research of KAT5.
MRGBP; ZBTB8A; RUVBL1; Myod1; CBX8