Recombinant Human KAT5 Protein, GST-tagged
Cat.No. : | KAT5-5258H |
Product Overview : | Human HTATIP full-length ORF ( AAH00166, 1 a.a. - 461 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 76.34 kDa |
AA Sequence : | MAEVGEIIEGCRLPVLRRNQDNEDE WPLAEILSVKDISGRKLFYVHYIDF NKRLDEWVTHERLDLKKIQFPKKEA KTPTKNGLPGSRPGSPEREVKRKVE VVSPATPVPSETAPASVFPQNGAAR RAVAAQPGRKRKSNCLGTDEDSQDS SDGIPSAPRMTGSLVSDRSHDDIVT RMKNIECIELGRHRLKPWYFSPYPQ ELTTLPVLYLCEFCLKYGRSLKCLQ RHLTKCDLRHPPGNEIYRKGTISFF EIDGRKNKSYSQNLCLLAKCFLDHK TLYYDTDPFLFYVMTEYDCKGFHIV GYFSKEKESTEDYNVACILTLPPYQ RRGYGKLLIEFSYELSKVEGKTGTP EKPLSDLGLLSYRSYWSQTILEILM GLKSESGERPQITINEISEITSIKK EDVISTLQYLNLINYYKGQYILTLS EDIVDGHERAMLKRLLRIDSKCLHF TPKDWSKRGKW |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | KAT5 K(lysine) acetyltransferase 5 [ Homo sapiens ] |
Official Symbol : | KAT5 |
Synonyms : | KAT5; K(lysine) acetyltransferase 5; HIV 1 Tat interactive protein, 60kDa , HTATIP; histone acetyltransferase KAT5; cPLA2; ESA1; HTATIP1; K acetyltransferase 5; PLIP; Tat interacting protein; 60kDa; TIP60; K-acetyltransferase 5; cPLA2 interacting protein; lysine acetyltransferase 5; cPLA(2)-interacting protein; 60 kDa Tat-interactive protein; Tat interacting protein, 60kDa; histone acetyltransferase HTATIP; HIV-1 Tat interactive protein, 60kDa; TIP; HTATIP; |
Gene ID : | 10524 |
mRNA Refseq : | NM_001206833 |
Protein Refseq : | NP_001193762 |
MIM : | 601409 |
UniProt ID : | Q92993 |
Products Types
◆ Recombinant Protein | ||
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KAT5-021H | Recombinant Human KAT5 Protein, His-tagged | +Inquiry |
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KAT5-4702M | Recombinant Mouse KAT5 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
KAT5-5088HCL | Recombinant Human KAT5 293 Cell Lysate | +Inquiry |
KAT5-5089HCL | Recombinant Human KAT5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionIt acetylates histone H4, affecting chromatin structure.
Certain cancers have identified mutations in KAT5.
KAT5 regulates gene expression via histone acetylation.
It plays a key role in repairing DNA double-strand breaks.
Dysregulation of KAT5 is linked to cancer development.
Therapies are being developed to modulate KAT5 in cancer and neurodegenerative diseases.
KAT5 is located in both the nucleus and cytoplasm.
Customer Reviews (3)
Write a reviewProduct arrived quickly, perfect.
Reliable for experiments, quality.
Great quality, worked well.
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