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Recombinant Human KAT5 Protein, GST-tagged

Cat.No. : KAT5-5258H
Product Overview : Human HTATIP full-length ORF ( AAH00166, 1 a.a. - 461 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 76.34 kDa
AA Sequence : MAEVGEIIEGCRLPVLRRNQDNEDE WPLAEILSVKDISGRKLFYVHYIDF NKRLDEWVTHERLDLKKIQFPKKEA KTPTKNGLPGSRPGSPEREVKRKVE VVSPATPVPSETAPASVFPQNGAAR RAVAAQPGRKRKSNCLGTDEDSQDS SDGIPSAPRMTGSLVSDRSHDDIVT RMKNIECIELGRHRLKPWYFSPYPQ ELTTLPVLYLCEFCLKYGRSLKCLQ RHLTKCDLRHPPGNEIYRKGTISFF EIDGRKNKSYSQNLCLLAKCFLDHK TLYYDTDPFLFYVMTEYDCKGFHIV GYFSKEKESTEDYNVACILTLPPYQ RRGYGKLLIEFSYELSKVEGKTGTP EKPLSDLGLLSYRSYWSQTILEILM GLKSESGERPQITINEISEITSIKK EDVISTLQYLNLINYYKGQYILTLS EDIVDGHERAMLKRLLRIDSKCLHF TPKDWSKRGKW
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : KAT5 K(lysine) acetyltransferase 5 [ Homo sapiens ]
Official Symbol : KAT5
Synonyms : KAT5; K(lysine) acetyltransferase 5; HIV 1 Tat interactive protein, 60kDa , HTATIP; histone acetyltransferase KAT5; cPLA2; ESA1; HTATIP1; K acetyltransferase 5; PLIP; Tat interacting protein; 60kDa; TIP60; K-acetyltransferase 5; cPLA2 interacting protein; lysine acetyltransferase 5; cPLA(2)-interacting protein; 60 kDa Tat-interactive protein; Tat interacting protein, 60kDa; histone acetyltransferase HTATIP; HIV-1 Tat interactive protein, 60kDa; TIP; HTATIP;
Gene ID : 10524
mRNA Refseq : NM_001206833
Protein Refseq : NP_001193762
MIM : 601409
UniProt ID : Q92993

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What is the significance of KAT5 in the acetylation of histones? 08/06/2022

It acetylates histone H4, affecting chromatin structure.

Are there known genetic mutations in KAT5 associated with specific diseases? 06/07/2021

Certain cancers have identified mutations in KAT5.

What is the primary role of KAT5 in the regulation of gene expression? 08/05/2020

KAT5 regulates gene expression via histone acetylation.

How does KAT5 contribute to DNA repair processes? 07/01/2020

It plays a key role in repairing DNA double-strand breaks.

How is KAT5 implicated in cancer development and progression? 09/30/2019

Dysregulation of KAT5 is linked to cancer development.

What therapeutic strategies are being explored that involve modulation of KAT5 for disease treatment? 04/03/2019

Therapies are being developed to modulate KAT5 in cancer and neurodegenerative diseases.

In which cellular compartments is KAT5 predominantly found? 07/26/2018

KAT5 is located in both the nucleus and cytoplasm.

Customer Reviews (3)

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Reviews
07/06/2022

    Product arrived quickly, perfect.

    05/17/2021

      Reliable for experiments, quality.

      01/28/2021

        Great quality, worked well.

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