ldhb
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  • Official Full Name
  • lactate dehydrogenase B
  • Background
  • This gene encodes an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on the X chromosome and on chromosome. Multiple alternatively spliced variants, encoding the same protein, have been identified.
  • Synonyms
  • LDHB; lactate dehydrogenase B; L-lactate dehydrogenase B chain; LDH heart subunit; lactate dehydrogenase H chain; renal carcinoma antigen NY-REN-46; LDH-B; LDH-H; LDHBD; TRG-5
Cat.#:LDHB-424HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human LDHB Protein, MYC/DDK-tagged
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Cat.#:LDHB-2570HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Lactate Dehydrogenase B, His-tagged
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Cat.#:LDHB-257HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human LDHB, GST-tagged
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Cat.#:LDHB-26865THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LDHB, His-tagged
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Cat.#:LDHB-931HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LDHB Protein, His-tagged
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Cat.#:Ldhb-1817MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ldhb protein, His-tagged
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Cat.#:LDHB-9022MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse LDHB Protein
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Cat.#:Ldhb-1818RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ldhb protein, His-tagged
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Cat.#:LDHB-3370RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat LDHB Protein
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Cat.#:LDHB-2488RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey LDHB Protein, His-tagged
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Cat.#:LDHB-5751CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken LDHB
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Cat.#:LDHB-82CTag:N/A
Source (Host):E. coliSpecies:Chicken
Product nameRecombinant Chicken Lactate Dehydrogenase B
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Cat.#:LDH2-123HTag:N/A
Source (Host):Human HeartSpecies:Human
Product nameNative Human Lactate Dehydrogenase 2
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Cat.#:LDH2-220HTag:N/A
Source (Host):Human erythrocytesSpecies:Human
Product nameNative Human Lactate Dehydrogenase 2
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Cat.#:LDHB-4788HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human LDHB 293 Cell Lysate
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Cat.#:Kit-0510Tag:N/A
Source (Host):Species:
Product nameLactate Dehydrogenase B (LDHB) Activity Assay Kit
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Involved Pathway

LDHB involved in several pathways and played different roles in them. We selected most pathways LDHB participated on our site, such as Glycolysis / Gluconeogenesis, Cysteine and methionine metabolism, Pyruvate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with LDHB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycolysis / Gluconeogenesis
FBP2; AKR1A1; G6PCA.1; FBP1A; GALM; ADH2-2; ALDH7A1; PGAM1; PCK1; ALDOC
Cysteine and methionine metabolism
ENOPH1; AHCY; LDHAL6B; LDHB; MDH1AA; MDH2; TAT; IL4I1; GOT2A; MRI1
Pyruvate metabolism
PCXB; PDHA1B; ACACB; GRHPRA; HAGH; ACAT1; LDHBA; ACAT2; PKLR; ACSS2L
Propanoate metabolism
LDHBB; ACSS3; SUCLG2; PCCA; ACAT2; LDHAL6A; BCKDHB; ACSS1; LDHAL6B; ALDH6A1
Metabolic pathways
ACLY; SRM; ACSL1B; ITPKA; PLA2G3; GALNTL6; NADKD1; ABO; BPNT1; PON1
Glucagon signaling pathway
CAMK2A; PHKB; G6PC; PRKAG1; CALM3; AKT2; PRMT1; PRKAB1; PYGM; AKT1

Protein Function

LDHB has several biochemical functions, for example, L-lactate dehydrogenase activity, NAD binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LDHB itself. We selected most functions LDHB had, and list some proteins which have the same functions with LDHB. You can find most of the proteins on our site.
Function
Related Protein
Function L-lactate dehydrogenase activity
Related Protein LDHA; LDHAL6A; LDHAL6B; LDHBB; LDHBA; LDHC; LDHB
Function NAD binding
Related Protein GRHPRA; GPD1A; AOX3; HADHA; AOX4; GPD1L; ME3; GAPDHS; TESCA; SORD
Function identical protein binding
Related Protein CHEK2; ABCD1; SHANK1; UBQLN1; DPP9; PYCARD; PRMT1; C1S; FBXW7; IFIT3
Function kinase binding
Related Protein RASGRP3; LDHA; BCL10; TENC1; SP100; JAKMIP2; WWC3; PARP16; PRKCD; HAP1
Function protein binding
Related Protein ITGAV; TSSK3; GEM; MTRR; TBX24; CAMTA2; MECOM; PHF19; GRB2; DAB1

Interacting Protein

LDHB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LDHB here. Most of them are supplied by our site. Hope this information will be useful for your research of LDHB.
LDHA; PEX5; VCAM1; LRRK2; TERF1; RAC3; YWHAZ; TBK1; LDHA; artM4