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Official Full Name mastermind-like 1 (Drosophila)
Background This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. [provided by RefSeq, Jul 2008]
Synonyms MAML1; mastermind-like 1 (Drosophila); Mam1; Mam-1; mastermind-like protein 1; mastermind homolog;
    • Species :
    • Human
    • Mouse
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • MYC/DDK
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Maml1-238M Recombinant Mouse Maml1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human MAML1-3627H Recombinant Human MAML1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human MAML1-330H Recombinant Human MAML1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse MAML1-9475M Recombinant Mouse MAML1 Protein Mammalian Cell His

    MAML1 involved in several pathways and played different roles in them. We selected most pathways MAML1 participated on our site, such as Notch signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAML1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Notch signaling pathway NUMB; CNTN6; CTBP2A; RBPJA; MIB1; EP300; HER12; DLL4; APH1B; MFNG

    MAML1 has several biochemical functions, for example, peptide antigen binding, protein kinase binding, transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MAML1 itself. We selected most functions MAML1 had, and list some proteins which have the same functions with MAML1. You can find most of the proteins on our site.

    Function Related Protein
    peptide antigen binding MHC1UBA; TUBB3; HLA-B; HLA-DPA1; DHCR24; MHC1ZDA; MHC1UKA; HLA-G; HLA-DRB1; H2-Q10
    protein kinase binding GCSAM; LIMS1; NBEA; AURKA; SQSTM1; TRPV4; GATA6; SKI; FAM83D; ADAM10
    transcription coactivator activity HAND1; ZEB1; PCBD1; UTF1; BCL10; HSF2; MED16; USP16; NFE2; MED14

    MAML1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAML1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAML1.


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