Recombinant Mouse Maml1 Protein, MYC/DDK-tagged
Cat.No. : | Maml1-238M |
Product Overview : | Purified recombinant protein of full-length mouse mastermind like transcriptional coactivator 1 (Maml1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 108.2 kDa |
Purity : | >80%, as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Maml1 mastermind like transcriptional coactivator 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Maml1 |
Synonyms : | Maml1; mastermind like transcriptional coactivator 1; Mam1; Mam-1; AI644666; AW743257; mKIAA0200; D930008C07Rik; mastermind-like protein 1; maml1; mastermind like 1 |
Gene ID : | 103806 |
mRNA Refseq : | NM_175334 |
Protein Refseq : | NP_780543 |
UniProt ID : | Q6T264 |
Products Types
◆ Recombinant Protein | ||
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MAML1-330H | Recombinant Human MAML1 Protein, MYC/DDK-tagged | +Inquiry |
MAML1-5310M | Recombinant Mouse MAML1 Protein, His (Fc)-Avi-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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