Recombinant Human MAML1 Protein, MYC/DDK-tagged

• Cat.No.: MAML1-330H
• Product Overview: Recombinant human MAML1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. [provided by RefSeq, Jul 2008]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 107.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: mastermind like transcriptional coactivator 1 [ Homo sapiens ]
• Official Symbol: MAML1
• Synonyms: Mam-1; Mam1
• Gene ID: 9794
• Protein Refseq: NP_055572
• MIM: 605424