mcm7
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  • Official Full Name
  • minichromosome maintenance complex component 7
  • Background
  • The minichromosome maintenance (MCM) 2-7 proteins are a family of six related proteins required for the initiation and elongation of DNA replication. MCM2-7 bind together to form the heterohexameric MCM complex that is thought to act as a replicative heli
  • Synonyms
  • MCM7; minichromosome maintenance complex component 7; MCM2, MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) , minichromosome maintenance deficient (S. cerevisiae) 7; DNA replication licensing factor MCM7; CDC47; CDC47 homolog; homolog of S.
Cat.#:MCM7-4517HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MCM7 Protein, GST-tagged
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Cat.#:MCM7-28043THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human MCM7
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Cat.#:MCM7-427HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human minichromosome maintenance complex component 7, His-tagged
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Cat.#:MCM7-5028HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MCM7, His-tagged
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Cat.#:MCM7-11849ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MCM7
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Cat.#:MCM7-4415HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MCM7 293 Cell Lysate
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Involved Pathway

MCM7 involved in several pathways and played different roles in them. We selected most pathways MCM7 participated on our site, such as DNA replication, Cell cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with MCM7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
DNA replication
DNA2; POLA1; LIG1; GMNN; MCM6; RPA2; GINS4; DBF4; POLE3; RNASEH2C
Cell cycle
NUMA1; GADD45AB; RAD50; MCM3L; HTATIP; E2F2; CEP76; RBBP4; CDK7; CUL1

Protein Function

MCM7 has several biochemical functions, for example, ATP binding, contributes_to ATP-dependent DNA helicase activity, contributes_to DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MCM7 itself. We selected most functions MCM7 had, and list some proteins which have the same functions with MCM7. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein DDX21; EHD4; VSIG8B; MAP2K3; CDK5; EPHA2A; ATP6AP1; MTHFD1L; MAP3K2; KIF1C
Function contributes_to ATP-dependent DNA helicase activity
Related Protein NBN; MRE11A; MCM7; MCM4; RAD50; MCM6
Function contributes_to DNA binding
Related Protein MLXIPL; GTF3C2; GTF3C4; SMAD2; MCM7; GTF3C5; GTF3C3; CLOCKA; NFE2L2A; ARNTL1B
Function protein binding
Related Protein TTC37; TCEA1; TPD52; MAP3K14; ACCS; DAO; KCNQ1; RPS6KA3; CA2; GZMA
Function single-stranded DNA binding
Related Protein SSBP3; ERCC4; FUBP1; SSBP3A; OBFC1; HMGB2; SUB1; LRPPRC; XRCC3; ANXA1

Interacting Protein

MCM7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MCM7 here. Most of them are supplied by our site. Hope this information will be useful for your research of MCM7.
MCM4; MCMBP

MCM7 Related Articles

Borgogna, C; Lanfredini, S; et al. Improved detection reveals active beta-papillomavirus infection in skin lesions from kidney transplant recipients. MODERN PATHOLOGY 27:1101-1115(2014).
Ishibashi, Y; Kinugasa, T; et al. Minichromosome Maintenance Protein 7 Is a Risk Factor for Recurrence in Patients with Dukes C Colorectal Cancer. ANTICANCER RESEARCH 34:4569-4575(2014).