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Recombinant Human MCM7 Protein, GST-tagged

Cat.No. : MCM7-4517H
Product Overview : Human MCM7 full-length ORF ( AAH09398, 1 a.a. - 389 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 68.53 kDa
AA Sequence : MALKDYALEKEKVKKFLQEFYQDDE LGKKQFKYGNQLVRLAHREQVALYV DLDDVAEDDPELVDSICENARRYAK LFADAVQELLPQYKEREVVNKDVLD VYIEHRLMMEQRSRDPGMVRSPQNQ YPAELMRRFELYFQGPSSSKPRVIR EVRADSVGKLVTVRGIVTRVSEVKP KMVVATYTCDQCGAETYQPIQSPTF MPLIMCPSQECQTNRSGGRLYLQTR GSRFIKFQEMKMQEHSDQVPVGNIP RSITVLVEGENTRIAQPGDHVSVTG IFLPILRTGFRQVVQGLLSETYLEA HRIVKMNKSEDDESGAGELTREELR QIADVIFATVRELVSGGRSVRFSEA EQRCVSRGFTPAQFQAALDEYEELN VWQVNASRTRITFV
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : MCM7 minichromosome maintenance complex component 7 [ Homo sapiens ]
Official Symbol : MCM7
Synonyms : MCM7; minichromosome maintenance complex component 7; MCM2, MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) , minichromosome maintenance deficient (S. cerevisiae) 7; DNA replication licensing factor MCM7; CDC47; CDC47 homolog; homolog of S. cerevisiae Cdc47; minichromosome maintenance deficient 7; MCM2; P85MCM; P1CDC47; PNAS146; P1.1-MCM3;
Gene ID : 4176
mRNA Refseq : NM_005916
Protein Refseq : NP_005907
MIM : 600592
UniProt ID : P33993

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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