Recombinant Human MCM7 Protein, GST-tagged
Cat.No. : | MCM7-4517H |
Product Overview : | Human MCM7 full-length ORF ( AAH09398, 1 a.a. - 389 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 68.53 kDa |
AA Sequence : | MALKDYALEKEKVKKFLQEFYQDDE LGKKQFKYGNQLVRLAHREQVALYV DLDDVAEDDPELVDSICENARRYAK LFADAVQELLPQYKEREVVNKDVLD VYIEHRLMMEQRSRDPGMVRSPQNQ YPAELMRRFELYFQGPSSSKPRVIR EVRADSVGKLVTVRGIVTRVSEVKP KMVVATYTCDQCGAETYQPIQSPTF MPLIMCPSQECQTNRSGGRLYLQTR GSRFIKFQEMKMQEHSDQVPVGNIP RSITVLVEGENTRIAQPGDHVSVTG IFLPILRTGFRQVVQGLLSETYLEA HRIVKMNKSEDDESGAGELTREELR QIADVIFATVRELVSGGRSVRFSEA EQRCVSRGFTPAQFQAALDEYEELN VWQVNASRTRITFV |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | MCM7 minichromosome maintenance complex component 7 [ Homo sapiens ] |
Official Symbol : | MCM7 |
Synonyms : | MCM7; minichromosome maintenance complex component 7; MCM2, MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) , minichromosome maintenance deficient (S. cerevisiae) 7; DNA replication licensing factor MCM7; CDC47; CDC47 homolog; homolog of S. cerevisiae Cdc47; minichromosome maintenance deficient 7; MCM2; P85MCM; P1CDC47; PNAS146; P1.1-MCM3; |
Gene ID : | 4176 |
mRNA Refseq : | NM_005916 |
Protein Refseq : | NP_005907 |
MIM : | 600592 |
UniProt ID : | P33993 |
Products Types
◆ Recombinant Protein | ||
MCM7-1383H | Recombinant Human MCM7 Protein, His (Fc)-Avi-tagged | +Inquiry |
Mcm7-3998M | Recombinant Mouse Mcm7 Protein, Myc/DDK-tagged | +Inquiry |
MCM7-01H | Recombinant Human MCM7 Protein, Myc/DDK-tagged | +Inquiry |
MCM7-28043TH | Recombinant Human MCM7 | +Inquiry |
MCM7-11849Z | Recombinant Zebrafish MCM7 | +Inquiry |
◆ Lysates | ||
MCM7-4415HCL | Recombinant Human MCM7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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