mlf1
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  • Official Full Name
  • myeloid leukemia factor 1
  • Background
  • This gene encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. Translocations between this gene and nucleophosmin have been associated with myelodysplastic syndrome and acute myeloid leukemia. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • MLF1; myeloid leukemia factor 1; myeloid leukemia factor 1 variant 1; myeloid leukemia factor 1 variant 2; myeloid leukemia factor 1 variant 3; Hls7; MLF1_HUMAN; Myelodysplasia myeloid leukemia factor 1; Myelodysplasia-myeloid leukemia factor 1; OTTHUMP00000213453; OTTHUMP00000213454; OTTHUMP00000213483; OTTHUMP00000213484; OTTHUMP00000213485; OTTHUMP00000213486; OTTHUMP00000213487; OTTHUMP00000213488; OTTHUMP00000213492; OTTHUMP00000213493; OTTHUMP00000213494
Cat.#:MLF1-149HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MLF1 protein, T7-tagged
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Cat.#:MLF1-2390HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MLF1 protein, GST-tagged
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Cat.#:MLF1-29154THTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MLF1, T7 -tagged
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Cat.#:MLF1-3438HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MLF1 protein, His-tagged
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Cat.#:MLF1-2780RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey MLF1 Protein, His-tagged
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Cat.#:MLF1-2944HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Myeloid Leukemia Factor 1, T7-tagged
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Cat.#:MLF1-4297HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MLF1 293 Cell Lysate
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Involved Pathway

MLF1 involved in several pathways and played different roles in them. We selected most pathways MLF1 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with MLF1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Transcriptional misregulation in cancer
TMPRSS2; MLL1; HIST1H3H; EYA1; GRIA3; MLLT1; CD86; NUPR1; ZBTB16; GOLPH3

Protein Function

MLF1 has several biochemical functions, for example, DNA binding, protein binding, protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MLF1 itself. We selected most functions MLF1 had, and list some proteins which have the same functions with MLF1. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ZFP553; VEZF1; ZNF550; HELT; HOXA11A; TCEANC; MECOM; POLE; SCML2; PAX2B
Function protein binding
Related Protein NDFIP2; KRT81; EPHA2; TRIM39; SPANXA1; NPLOC4; SMARCB1; RAD1; PPARGC1A; CNOT3
Function protein domain specific binding
Related Protein PLXND1; VPS4A; PRKAR2B; HMGB2; STXBP1; PKD1; DYNLL1; SLC34A2; HNRNPM; XPA

Interacting Protein

MLF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MLF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MLF1.
DNAJB6; YWHAE; a8k1f4_human; a8k251_human; b2rc52_human; b4de84_human; HAX1; IRS4; GNB5; TET3; PSMD3; ZBED4; REC8; BAG2; BAG3; MOS