nbl1
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  • Official Full Name
  • neuroblastoma, suppression of tumorigenicity 1
  • Background
  • This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins a
  • Synonyms
  • NBL1; neuroblastoma, suppression of tumorigenicity 1; neuroblastoma suppressor of tumorigenicity 1; D1S1733E; DAN; DAN domain family member 1; DAND 1; DAND1; Differential screening selected gene aberrant in neuroblastoma; MGC8972; NB; NBL 1; Neuroblastoma candidate region suppression of tumorigenicity 1; Neuroblastoma suppression of tumorigenicity 1; NO 3; NO3; Zinc finger protein DAN; N03; OTTMUSP00000010476; Dana; D4H1S1733E
Cat.#:NBL1-1599HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human Neuroblastoma, Suppression of Tumorigenicity 1
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Cat.#:NBL1-681HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human NBL1, Fc tagged
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Cat.#:NBL1-682HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human NBL1, His tagged
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Cat.#:NBL1-7523HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NBL1, His-tagged
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Cat.#:Nbl1-5690MTag:His
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Neuroblastoma, Suppression Of Tumorigenicity 1, His-tagged
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Cat.#:NBL1-942MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse NBL1 Protein, His-tagged
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Cat.#:NBL1-3911RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat NBL1 Protein
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Cat.#:NBL1-5725CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken NBL1
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Cat.#:NBL1-11824ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish NBL1
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Cat.#:NBL1-2987HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human NBL1 cell lysate
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Cat.#:NBL1-1627MCLTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse NBL1 cell lysate
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Involved Pathway

NBL1 involved in several pathways and played different roles in them. We selected most pathways NBL1 participated on our site, such as TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NBL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
TGF-beta signaling pathway
BMP7; RBX1; ROCK2B; BMPR1B; SKP1; BMP5; BMPR1BB; RBL1; BMP8B; PPP2R1A

Protein Function

NBL1 has several biochemical functions, for example, BMP binding, morphogen activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NBL1 itself. We selected most functions NBL1 had, and list some proteins which have the same functions with NBL1. You can find most of the proteins on our site.
Function
Related Protein
Function BMP binding
Related Protein CER1; GREM2; HFE2; GDF5; TCAP; NBL1; BMPR2; GREM1
Function morphogen activity
Related Protein GREM1; CER1; NODAL; Shh; DAND5; NBL1
Function protein binding
Related Protein AGPAT5; GSTP1; RPF1; SCRIB; ZNF302; ZBTB6; NLK; TMUB2; UBE2E1; MYEF2
Function protein homodimerization activity
Related Protein KCNN2; GPD1A; HIF1AN; RAG1; GDF6; EPHX2; NADK2; HSPB6; ODZ4; ANO2

Interacting Protein

NBL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NBL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NBL1.
NCS1; ZMIZ2; UBQLN1; UBQLN1