NME1 Protein, NME/NM23 nucleoside diphosphate kinase 1


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Official Full Name NME/NM23 nucleoside diphosphate kinase 1
Background This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of A (encoded by this gene) and B (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]
Synonyms NME1; NME/NM23 nucleoside diphosphate kinase 1; NB; AWD; NBS; GAAD; NDKA; NM23; NDPKA; NDPK-A; NM23-H1; nucleoside diphosphate kinase A; NDP kinase A; granzyme A-activated DNase; metastasis inhibition factor nm23; tumor metastatic process-associated protein; non-metastatic cells 1, protein (NM23A) expressed in;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NME1-1310H Recombinant Human NME1, GST-tagged E.coli GST
    Human NME1-192H Recombinant Human NME1 protein E.coli N/A
    Human NME1-28097TH Recombinant Human NME1 E.coli N/A
    Human NME1-3792HCL Recombinant Human NME1 293 Cell Lysate HEK293 N/A
    Human NME1-478H Recombinant Human NME1 protein, His-tagged E.coli His
    Human NME1-485H Recombinant Human Non-metastatic Cells 1, Protein (NM23A) E.coli N/A
    Human NME1-5924H Recombinant Human NME1 Protein, GST-tagged Wheat Germ GST
    Human NME1-748H Recombinant Human NME1 Protein, His-tagged E.coli His
    Mouse NME1-10738M Recombinant Mouse NME1 Protein Mammalian Cell His
    Mouse Nme1-1719M Recombinant Mouse Nme1 protein, His-tagged E.coli His
    Rat NME1-4003R Recombinant Rat NME1 Protein Mammalian Cell His
    Rhesus Macaque NME1-3054R Recombinant Rhesus monkey NME1 Protein, His-tagged Mammalian Cell His
    Chicken NME1-4500C Recombinant Chicken NME1 Mammalian Cell His

    NME1 involved in several pathways and played different roles in them. We selected most pathways NME1 participated on our site, such as Purine metabolism, Pyrimidine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with NME1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Purine metabolism AK8; NT5E; ADSL; RRM1; PDE4B; HDDC3; ADK; POLR2A; ZNRD1; POLR2E
    Pyrimidine metabolism CANT1; NME2B.2; CTPS2; POLR1A; POLR1C; UPP1; PNP6; PRIM1; NME7; CAD
    Metabolic pathways PTGES3A; COX10; ST6GALNAC1; CBR1; CMAS; DOLK; HMBSB; TKTL2; POLE4; ST6GAL2

    NME1 has several biochemical functions, for example, ATP binding, GTP binding, deoxyribonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NME1 itself. We selected most functions NME1 had, and list some proteins which have the same functions with NME1. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding BMPR1BA; TRPV1; IGHMBP2; BBS12; PGK1; PET112L; MARK1; DDX6; ATP7A; IDE
    deoxyribonuclease activity TATDN2; TATDN1; DNASE1L1; NME1; DNASE1L2; DNASE1L3; DNASE1L3L; TATDN3; ENDOG
    identical protein binding PCNA; CDC42BPA; NPR2; CLDN9; ATG101; TTR; NDE1; PRMT1; NEFL; STAT6
    magnesium ion binding HACL1; MAP3K5; ENOSF1; PPM1N; RPS6KA4; CIB3; MAP3K6; LATS1; STK11; MTHFD2
    nucleoside diphosphate kinase activity NME2B.1; CMPK; TXNDC3; NME9; NME5; NME7; AK9; CMPK2; NME2; CMPK1
    poly(A) RNA binding HIST1H4M; RPL5A; FAM133B; LARP2; RPS27.2; SFPQ; RPS12; BCCIP; HSPA9; DDX27
    protein binding TAF11; PAK2; DNAJA4; FAM64A; RBMX; PARK7; FAM114A1; C9orf86; H3F3A; METTL1
    ribosomal small subunit binding PTCD3; MTIF3; DHX29; PIM1; NPM1; ERAL1; DDX3X; CPEB2; NME1

    NME1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NME1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NME1.

    N/A; POLR1C; NME4; NME3

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