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Recombinant Full Length Human NME1 Protein, C-Flag-tagged

Cat.No. : NME1-910HFL
Product Overview : Recombinant Full Length Human NME1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.
  • Specification
  • Gene Information
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Description : This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Source : Mammalian cells
Species : Human
Tag : Flag
Form : 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 19.5 kDa
AA Sequence : MVLLSTLGIVFQGEGPPISSCDTGT MANCERTFIAIKPDGVQRGLVGEII KRFEQKGFRLVGLKFMQASE DLLKEHYVDLKDRPFFAGLVKYMHS GPVVAMVWEGLNVVKTGRVMLGETN PADSKPGTIRGDFCIQVGRN
IIHGSDSVESAEKEIGLWFHPEELV DYTSCAQNWIYETRTRPLEQKLISE EDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining.
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade.
Concentration : >50 ug/mL as determined by microplate BCA method.
Preparation : Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families : Druggable Genome, Stem cell - Pluripotency
Protein Pathways : Metabolic pathways, Purine metabolism, Pyrimidine metabolism
Gene Name : NME1 NME/NM23 nucleoside diphosphate kinase 1 [ Homo sapiens (human) ]
Official Symbol : NME1
Synonyms : NB; AWD; NBS; GAAD; NDKA; NM23; NDPKA; NDPK-A; NM23-H1
Gene ID : 4830
mRNA Refseq : NM_198175.1
Protein Refseq : NP_937818.1
MIM : 156490
UniProt ID : P15531

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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