|Official Full Name||nudix (nucleoside diphosphate linked moiety X)-type motif 2|
|Background||This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified.|
|Synonyms||NUDT2; nudix (nucleoside diphosphate linked moiety X)-type motif 2; APAH1; bis(5-nucleosyl)-tetraphosphatase [asymmetrical]; Ap4A hydrolase 1; Ap4Aase; bis(5 nucleosyl) tetraphosphatase (asymmetrical); diadenosine 5; 5 P1; P4 tetraphosphate pyrophosphohydrolase; diadenosine tetraphosphatase; 2310051L06Rik; AA939917; Ap4A hydrolase; APAH 1; Bis(5 nucleosyl) tetraphosphatase [asymmetrical]; Diadenosine 5,5 P1,P4 tetraphosphate asymmetrical hydrolase; Diadenosine 5,5-P1,P4-tetraphosphate pyrophosphohydrolase; EC 188.8.131.52; MGC10404; Nucleoside diphosphate linked moiety X motif 2; Nudix motif 2; Nudix-type motif 2; NUDT 2; OTTHUMP00000021256; OTTHUMP00000021257; OTTHUMP00000021258; OTTHUMP00000021259; nucleoside diphosphate-linked moiety X motif 2; bis(5-nucleosyl|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
NUDT2 involved in several pathways and played different roles in them. We selected most pathways NUDT2 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Purine metabolism||ADPRM; UOX; NME2B.2; NT5C2B; POLR1B; POLE2; IMPDH1B; PDE4C; POLR2GL; PDE7B|
|Pyrimidine metabolism||ITPA; POLR2A; TK1; UMPS; CANT1A; NME2A; TWISTNB; POLR3K; CMPK1; TK2|
NUDT2 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDT2 itself. We selected most functions NUDT2 had, and list some proteins which have the same functions with NUDT2. You can find most of the proteins on our site.
|GTP binding||ARF3; DIRAS1; ARF4; ARF1L; EFTUD2; GNL2; DNM1; GLUD1; SEPT9B; RHOF|
|bis(5-nucleosyl)-tetraphosphatase (asymmetrical) activity||NUDT2|
|bis(5-nucleosyl)-tetraphosphatase (symmetrical) activity||NUDT2|
|protein binding||PRL2C2; APC; RASSF9; NOTCH2NL; TBC1D1; ANK1; KCTD5; CD14; RWDD1; RNF13|
NUDT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDT2.