nxt1
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  • Official Full Name
  • NTF2-like export factor 1
  • Background
  • The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.
  • Synonyms
  • NXT1; NTF2-like export factor 1; NTX2 like export factor1; NTF2-related export protein 1; MTR2; P15; NTF2 like export factor 1; NTF2 related export protein 1; NUTF like export factor 1; NXT1_HUMAN; Protein P15; OTTHUMP00000030420; NTX2-like export factor1; NUTF-like export factor 1
Cat.#:NXT1-1431HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NXT1, GST-tagged
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Cat.#:NXT1-210HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NXT1 protein, T7-tagged
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Cat.#:NXT1-28306THTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NXT1, T7 -tagged
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Cat.#:NXT1-2951HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NTF2-like Export Factor 1, T7-tagged
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Cat.#:NXT1-29564THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NXT1, His-tagged
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Cat.#:NXT1-3523HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NTF2-Like Export Factor 1, His-tagged
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Cat.#:NXT1-3145RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey NXT1 Protein, His-tagged
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Cat.#:NXT1-3618HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human NXT1 293 Cell Lysate
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Involved Pathway

NXT1 involved in several pathways and played different roles in them. We selected most pathways NXT1 participated on our site, such as Ribosome biogenesis in eukaryotes, RNA transport, mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NXT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ribosome biogenesis in eukaryotes
WDR75; WDR3; WDR36; RCL1; UTP18; UTP14C; DKC1; CSNK2A2A; NXF2; PWP2
RNA transport
EIF4BB; THOC4; EIF3JA; UPF1; NCBP2; EIF3S10; THOC3; PABPC4; RNPS1; POP7
mRNA surveillance pathway
ETF1; UPF1; CPSF2; PPP2R5C; PPP2R5D; PPP2R2C; CPSF1; MSI2; CPSF5; PPP2R5EB
Influenza A
IFNGR1; IFN-a; LOC100686744; SOCS3; VDAC1; MAP2K3; IL8L2; IL8L1; MAP2K7; IL-8

Protein Function

NXT1 has several biochemical functions, for example, Ran GTPase binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NXT1 itself. We selected most functions NXT1 had, and list some proteins which have the same functions with NXT1. You can find most of the proteins on our site.
Function
Related Protein
Function Ran GTPase binding
Related Protein XPO4; TNPO2; IPO13; RANBP2; DPY19L2; RANBP10; BIRC5; RANGRF; KPNB1; NXT1
Function protein binding
Related Protein LARP4B; SUFU; SUV39H1; NLK; CHMP4C; EPC1; KLHL2; FAM50B; ZC3H14; MED9

Interacting Protein

NXT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NXT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NXT1.
NXF1; NXF3; STAU1; PAXIP1; Ranbp21; CHTOP