Recombinant Human NXT1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NXT1-5172H
• Product Overview: NXT1 MS Standard C13 and N15-labeled recombinant protein (NP_037380) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 15.8 kDa
• AA Sequence: MASVDFKTYVDQACRAAEEFVNVYY TTMDKRRRLLSRLYMGTATLVWNGN AVSGQESLSEFFEMLPSSEFQISVV DCQPVHDEATPSQTTVLVVICGSVK FEGNKQRDFNQNFILTAQASPSNTV WKIASDCFRFQDWASTRTRPLEQKL ISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NXT1 NTF2-like export factor 1 [ Homo sapiens (human) ]
• Official Symbol: NXT1
• Synonyms: NXT1; NTF2-like export factor 1; NTX2 like export factor1; NTF2-related export protein 1; MTR2; P15; protein p15; NTX2-like export factor1; NUTF-like export factor 1
• Gene ID: 29107
• mRNA Refseq: NM_013248
• Protein Refseq: NP_037380
• MIM: 605811
• UniProt ID: Q9UKK6