p2rx3
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  • Official Full Name
  • purinergic receptor P2X, ligand-gated ion channel, 3
  • Background
  • The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008]
  • Synonyms
  • P2RX3; purinergic receptor P2X, ligand-gated ion channel, 3; P2X3; P2X purinoceptor 3; ATP receptor; purinoceptor P2X3; P2X receptor, subunit 3; purinergic receptor P2X3;
Cat.#:P2RX3-9164HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human P2RX3, MYC/DDK-tagged
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Cat.#:P2RX3-1491HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human P2RX3, GST-tagged
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Cat.#:P2RX3-30538THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human P2RX3
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Cat.#:P2RX3-12267MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse P2RX3 Protein
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Cat.#:P2RX3-3500HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human P2RX3 293 Cell Lysate
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Involved Pathway

P2RX3 involved in several pathways and played different roles in them. We selected most pathways P2RX3 participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Calcium signaling pathway
MLCK2; AVPR1B; CALML5; PLCE1; HRH1; P2RX3B; TACR1A; F2R; CACNA1B; HTR2A
Neuroactive ligand-receptor interaction
C3AR1; HTR2B; S1PR2; HCRTR1; GHSRA; TRHR; DRD2B; HRH1; PTAFR; CHRNB3A

Protein Function

P2RX3 has several biochemical functions, for example, ATP binding, extracellular ATP-gated cation channel activity, purinergic nucleotide receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RX3 itself. We selected most functions P2RX3 had, and list some proteins which have the same functions with P2RX3. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein BAZ1B; TTBK1; NLRP10; RAD51; WEE1; ILF2; UBE2QL1; PCCA; DDX56; MAT2AL
Function extracellular ATP-gated cation channel activity
Related Protein P2RX3B; P2RX3A; P2RX7; P2RX8; P2RX1; P2RX2; P2RX5; P2RX4B; P2RX4A; P2RX4
Function purinergic nucleotide receptor activity
Related Protein P2RX4; P2RX4B; P2RX4A; P2RX2; P2RX1; P2RX7; P2RX3B; NNR; P2RX3A; P2RX8