Recombinant Human P2RX3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: P2RX3-1741H
• Product Overview: P2RX3 MS Standard C13 and N15-labeled recombinant protein (NP_002550) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the P2X purinergic receptor (purinoceptor) gene family which includes seven members (P2RX1 - P2RX7). P2X purinoceptors are a family of cation-permeable, ligand-gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP). The encoded protein is a subunit of the trimeric P2X3 receptor ion channel which is expressed by sensory or autonomic neurons. A deficiency of the orthologous protein in mice is associated with reduced pain-related behavior and urinary bladder hyporeflexia.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 44.1 kDa
• AA Sequence: MNCISDFFTYETTKSVVVKSWTIGI INRVVQLLIISYFVGWVFLHEKAYQ VRDTAIESSVVTKVKGSGLYANRVM DVSDYVTPPQGTSVFVIITKMIVTE NQMQGFCPESEEKYRCVSDSQCGPE RLPGGGILTGRCVNYSSVLRTCEIQ GWCPTEVDTVETPIMMEAENFTIFI KNSIRFPLFNFEKGNLLPNLTARDM KTCRFHPDKDPFCPILRVGDVVKFA GQDFAKLARTGGVLGIKIGWVCDLD KAWDQCIPKYSFTRLDSVSEKSSVS PGYNFRFAKYYKMENGSEYRTLLKA FGIRFDVLVYGNAGKFNIIPTIISS VAAFTSVGVGTVLCDIILLNFLKGA DQYKAKKFEEVNETTLKIAALTNPV YPSDQTTVEKQSTDSGAFSIGHTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: P2RX3 purinergic receptor P2X 3 [ Homo sapiens (human) ]
• Official Symbol: P2RX3
• Synonyms: P2RX3; purinergic receptor P2X, ligand-gated ion channel, 3; P2X purinoceptor 3; P2X3; ATP receptor; purinoceptor P2X3; P2X receptor, subunit 3; purinergic receptor P2X3; MGC129956
• Gene ID: 5024
• mRNA Refseq: NM_002559
• Protein Refseq: NP_002550
• MIM: 600843
• UniProt ID: P56373