pdcd6
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  • Official Full Name
  • programmed cell death 6
  • Background
  • This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant.
  • Synonyms
  • PDCD6; programmed cell death 6; programmed cell death protein 6; ALG 2; apoptosis linked gene 2; PEF1B; apoptosis-linked gene-2; apoptosis-linked gene 2 protein; probable calcium-binding protein ALG-2; ALG-2; MGC9123; FLJ46208; MGC111017; MGC119050
Cat.#:PDCD6-1595HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDCD6, GST-tagged
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Cat.#:PDCD6-30798THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDCD6, His-tagged
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Cat.#:PDCD6-3427HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDCD6 protein, His-tagged
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Cat.#:PDCD6-12537MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PDCD6 Protein
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Cat.#:PDCD6-776CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus PDCD6 Protein, His-tagged
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Cat.#:PDCD6-1824RTag:hIgG1
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey PDCD6 Protein, hIgG1-tagged
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Cat.#:PDCD6-1825RTag:hIgG4
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey PDCD6 Protein, hIgG4-tagged
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Cat.#:PDCD6-11187ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PDCD6
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Cat.#:PDCD6-3359HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PDCD6 293 Cell Lysate
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Protein Function

PDCD6 has several biochemical functions, for example, binding, bridging, calcium ion binding, calcium-dependent cysteine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PDCD6 itself. We selected most functions PDCD6 had, and list some proteins which have the same functions with PDCD6. You can find most of the proteins on our site.
Function
Related Protein
Function binding, bridging
Related Protein TRADD; PDCD6; GAS6
Function calcium ion binding
Related Protein EFHA1; ELTD1; CALU; NCALDB; CAPN13; FBN2; CDH5; PCDH1G9; CPNE6; MYL9
Function calcium-dependent cysteine-type endopeptidase activity
Related Protein CAPN2; CAPN11; CAPN3A; CAPN10; CAPN2B; SRI; PDCD6; CAPN12; CAPNS1A; CAPN13
Function calcium-dependent protein binding
Related Protein RBM22; CD209A; TSG101; NELF; MYO5A; NRXN1; SELP; ANXA1; S100A1; S100A6
Function identical protein binding
Related Protein KCNRG; HSP90AA1; TRADD; HAND2; MRFAP1L1; ABCD1; ACADM; SEPHS1; SIAH1; KDM6A
Function protein anchor
Related Protein SLC4A1; RAPSN; AKAP6; PDCD6; SUN5; ALG14; MYH9; NUP153; SUN3; CIB1
Function protein binding
Related Protein SNAP29; COPS8; ZNF490; CFL2; SARM1; ARPC3; GRHL2; Aatk; MAP2K3; RYK
Function protein dimerization activity
Related Protein NEUROG3; MITFA; LYL1; ATP6V1C2; TFAP2C; HNF1A; CELSR1; ID4; NEUROD6A; TXLNB
Function protein homodimerization activity
Related Protein ACVR1; BLOC1S6; IDE; CAMK2D; TOP2A; ANG; TSG101; NR2C1; SPPL2B; VOX

Interacting Protein

PDCD6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDCD6 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDCD6.
PEF1; PDCD6IP; PLSCR3