PDCD6

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PDCD6

Official Full Name programmed cell death 6
Background This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant.
Synonyms PDCD6; programmed cell death 6; programmed cell death protein 6; ALG 2; apoptosis linked gene 2; PEF1B; apoptosis-linked gene-2; apoptosis-linked gene 2 protein; probable calcium-binding protein ALG-2; ALG-2; MGC9123; FLJ46208; MGC111017; MGC119050
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rhesus monkey
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • hIgG1
    • hIgG4
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PDCD6-1595H Recombinant Human PDCD6, GST-tagged E.coli GST
    Human PDCD6-30798TH Recombinant Human PDCD6, His-tagged E.coli His
    Human PDCD6-3359HCL Recombinant Human PDCD6 293 Cell Lysate HEK293 N/A
    Human PDCD6-3427H Recombinant Human PDCD6 protein, His-tagged E.coli His
    Mouse PDCD6-12537M Recombinant Mouse PDCD6 Protein Mammalian Cell His
    Cynomolgus Monkey PDCD6-776C Recombinant Cynomolgus PDCD6 Protein, His-tagged Mammalian Cell His
    Rhesus monkey PDCD6-1824R Recombinant Rhesus Monkey PDCD6 Protein, hIgG1-tagged HEK293 hIgG1
    Rhesus monkey PDCD6-1825R Recombinant Rhesus Monkey PDCD6 Protein, hIgG4-tagged HEK293 hIgG4
    Zebrafish PDCD6-11187Z Recombinant Zebrafish PDCD6 Mammalian Cell His

    PDCD6 involved in several pathways and played different roles in them. We selected most pathways PDCD6 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDCD6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    PDCD6 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by PDCD6 itself. We selected most functions PDCD6 had, and list some proteins which have the same functions with PDCD6. You can find most of the proteins on our site.

    Function Related Protein
    binding, bridging GAS6; TRADD; PDCD6
    calcium ion binding MBL2; C1rb; PVALB1; PLS1; CELSR2; KCNIP2; PCDH2G5; PCDH2G10; PPEF1; KCNIP3B
    calcium-dependent cysteine-type endopeptidase activity CAPN1B; CAPN2; CAPN10; CAPN1A; CAPN5; CAPN2B; PDCD6; CAPNS1; CAPN3A; CAPN3
    calcium-dependent protein binding CCDC167; PDCD6; CD209A; KCNIP3; MBL2; STMN2; NRXN1; MASP1; A2M; CALM1
    identical protein binding COL1A2; NCAM1; ALDOB; TK1; ACY3; CHMP4B; CSK; SCUBE1; SMG9; CLDND
    protein anchor SUN5; ALG14; CIB1; MYH9; AKAP6; RAPSN; PDCD6; NUP153; SUN3; SUN1
    protein binding GATA3; MAP4K5; TMEM79; CCL11; RNF5; CEP290; TFIP11; GTPBP3; RAD9B; TSNAX
    protein dimerization activity POLR2J2; MNT; ANO7; TWIST1A; MESP1; PPP3CA; CLOCK; BHLHE41; TFE3A; ASCL1B
    protein homodimerization activity TIMELESS; CRTAM; PYCARD; IKBKB; BST2; OXA1L; Anks6; BHLHE40; CARD8; PRDX4

    PDCD6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDCD6 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDCD6.

    PEF1; PDCD6IP; PLSCR3

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