Recombinant Human PDCD6 protein, His-tagged

• Cat.No.: PDCD6-3427H
• Product Overview: Recombinant Human PDCD6(1-191aa) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-191 a.a.
• Description: Programmed cell death 6, also known as PDCD6, is calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant.
• Form: Liquid. In 10mM sodium citrate(pH 3.5) containing 40% glycerol
• Molecular Mass: 24.0 kDa (211aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSHMFDRENKAGV NFSEFTGVWK YITDWQNVFR TYDRDNSGMI DKNELKQALS GFGYRLSDQF HDILIRKFDR QGRGQIAFDD FIQGCIVLQR MAAYSYRPGP GAGPGPAAGA ALPDQSFLWN VFQRVDKDRS GVISDTELQQ ALSNGTWTPF NPVTVRSIISLTDIFRRYDT DQDGWIQVSY EQYLSMVFSI V
• Purity: >95% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: PDCD6 programmed cell death 6 [ Homo sapiens ]
• Official Symbol: PDCD6
• Synonyms: PDCD6; programmed cell death 6; programmed cell death protein 6; ALG 2; apoptosis linked gene 2; PEF1B; apoptosis-linked gene-2; apoptosis-linked gene 2 protein; probable calcium-binding protein ALG-2; ALG-2; MGC9123; FLJ46208; MGC111017; MGC119050
• Gene ID: 10016
• mRNA Refseq: NM_013232
• Protein Refseq: NP_037364
• MIM: 601057
• UniProt ID: O75340
• Chromosome Location: 5p15.33
• Function: binding, bridging; calcium ion binding; calcium ion binding; calcium-dependent protein binding; calcium-dependent protein binding; protein binding; protein dimerization activity; protein homodimerization activity