PIK3CD

Home / Products / PIK3CD

PIK3CD

Official Full Name phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Background Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.[provided by RefSeq, Jul 2010]
Synonyms PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta; APDS; PI3K; IMD14; p110D; P110DELTA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; PI3Kdelta; phosphoinositide-3-kinase C; PI3-kinase p110 subunit delta; ptdIns-3-kinase subunit p110-delta; phosphoinositide-3-kinase, catalytic, delta polypeptide variant p37delta; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform;
    • Species :
    • Chicken
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PIK3CD-1727H Recombinant Human PIK3CD protein, His & T7-tagged E.coli His/T7
    Human PIK3CD-1896H Recombinant Human Phosphoinositide-3-Kinase, Catalytic, Delta Polypeptide, His-tagged Sf9 Insect Cell His
    Human PIK3CD-29587TH Recombinant Human PIK3CD N/A
    Human PIK3CD-3187HCL Recombinant Human PIK3CD 293 Cell Lysate HEK293 N/A
    Human PIK3CD-52H Recombinant Human PIK3CD, GST-tagged Sf9 Insect Cell GST
    Chicken PIK3CD-1989C Recombinant Chicken PIK3CD Mammalian Cell His
    Zebrafish PIK3CD-11416Z Recombinant Zebrafish PIK3CD Mammalian Cell His

    PIK3CD involved in several pathways and played different roles in them. We selected most pathways PIK3CD participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIK3CD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Inositol phosphate metabolism PIP5K1BA; MTMR3; MTMR8; PLCH1; PIP5K1A; MTMR2; PLCD3A; IMPAD1; ITPKA; PIP4K2B
    ErbB signaling pathway MAPK10; BADB; PAK1; NRG2B; GSK3AA; PAK2B; NRAS; MAP2K2B; MAPK8; BRAF
    Ras signaling pathway CSF1; PLA2G4F; KSR2; RAC2; INS; IGF1R; PIK3R2; PIK3R3; RASA1; IGF1
    Rap signaling pathway KRAS; GNAS; PFN3; GRIN2A; PIK3R1; HGF; RAC1; ITGAM; KRIT1; FGF9
    cGMP-PKG signaling pathway MYLK; NFATC1; PRKG1; ITPR1; GNAI2; AKT1; VDAC3; SLC25A31; BNP; ATP2B1
    cAMP signaling pathway MC2R; PRKACB; CAMK2D; MAPK9; GHSR; HTR1B; PIK3R3; MLLT4; GPR119; CALML5
    Chemokine signaling pathway BRAF; RAF1; CRKL; CCR3; CCL27; PLCB2; PLCB3; CCL28; CCL23; NFKBIB
    HIF- signaling pathway PIK3CB; TFRC; STAT3; MAP2K2; MAP2K1; ARNT; PIK3CA; SLC2A1; HK1; CUL2
    FoxO signaling pathway GABARAPA; PTENB; RAG2; BRAF; FBXO25; KLF2B; Fasl; CCNB1; FOXO3B; PLK2B
    Phosphatidylinositol signaling system IP6K2; MTM1; PIP5K1BA; INPP5J; DGKD; PLCG2; PIK3C2B; CALM3B; PIP5K1B; PIK3CG
    Sphingolipid signaling pathway SMPD1; TNFRSF1A; SPTLC3; PPP2R5A; PLD2; AKT2; AKT1; BCL2; PPP2R1B; ROCK2
    Phospholipase D signaling pathway GRM3; AGPAT3; PLCB1; RALGDS; MRAS; MS4A2; LPAR4; GNAS; SOS1; PIK3CA
    mTOR signaling pathway PIK3R1; POLDIP3; MAPK1; RRN3; RB1CC1; ULK2; EIF4BB; RRAGCB; DEPDC6; RPS6KA3B
    PIK-Akt signaling pathway G6PC2; FGF21; IFNA2; MAP2K2; PPP2R5A; CCNE1; YWHAH; FGF19; IRS1; IFNA5
    AMPK signaling pathway TSC2; PCK1; SLC2A4; CCND1; CCNA2; IGF1R; FBP1; ULK1; AKT1; EEF2
    Apoptosis PLECA; DFFB; XIAP; APAF1; DIABLO; PRKACB; CASP3B; AKT1; DBNL; PRKACA
    Adrenergic signaling in cardiomyocytes ADRA1B; PPP2R2BB; CREM; PLN; ADCY9; CACNG3; ADCY6; CACNA1SA; ATP2B4; VMHCL
    VEGF signaling pathway PIK3CA; MAP2K2B; AKT2; NFATC2; BADB; MAPK3; PXNA; PPP3CA; MAP2K2A; PPP3R1B
    Osteoclast differentiation AKT2; TAB2; MAPK8; NCF1; NFATC1; OSCAR; PIK3R3; IL1R1; CYBA; FCGR3
    Focal adhesion LAMC2; ITGA2; ITGA3B; ITGB4; MYLPF; TNXB; VASP; THBS4B; IBSP; MAPK10
    Signaling pathways regulating pluripotency of stem cells HAND1; PCGF6; SKIL; APC; ACVR1B; REST; FZD6; MAP2K2; ISL1; PCGF3
    Platelet activation PIK3CA; GP5; NOS3; PRKACG; FYN; TBXA2R; MAPK13; BTK; AKT2; AKT1
    Toll-like receptor signaling pathway RIPK1; RAC1A; IFNB; MAP2K2B; TICAM2; PIK3R3; AKT2; PIK3CB; MAP2K6; MAPK12A
    Jak-STAT signaling pathway STAT6; GRB2; RAF1A; IL22; IFNB; STAT3; IL2RGA; CRFB2; LEPB; STAT4
    Natural killer cell mediated cytotoxicity RAC1; SH3BP2; FCER1G; Ifna11; HLA-A; KLRD1; RAET1D; RAC2; KIR3DL1; KIR3DL2
    T cell receptor signaling pathway BCL10; NFKBIE; MAP2K2; NCK1; Il2; GRB2; VAV1; LCK; LAT; DBNLB
    B cell receptor signaling pathway AKT1; PIK3R2; CARD11; DUSP6; AKT2; NFKBIB; RAP2A; PPP3R1; MAP2K1; KRAS
    Fc epsilon RI signaling pathway PIK3CD; VAV2; VAV3; MAP2K3; VAV1; IL3; MAP2K4; PLA2G4B; MS4A2; MAPK11
    Fc gamma R-mediated phagocytosis VAV1; PAK1; CFL1; SPHK2; WASF1; ASAP1; ASAP2; PTPRC; DOCK2; BIN1
    TNF signaling pathway TRAF1; CASP8; MMP9; MMP14; FADD; TRAF5; MMP3; TRAF3; MAP3K7IP3; MAPK3
    Leukocyte transendothelial migration CTNNA3; PLCG2; CLDN17; CXCR4; CLDN3; NOX3; EZR; MAPK11; RAC2; VASP
    Neurotrophin signaling pathway PSEN1; PIK3CB; NGFRAP1; GAB1; PTPN11; ZFP110; CAMK2D; CALM2; RPS6KA2; Fasl
    Cholinergic synapse MAPK3; AKT1; CREB3; GNG12; CHRNB4; AKT2; CAMK4; PRKACB; CHRNA7; GNAQ
    Inflammatory mediator regulation of TRP channels BDKRB2; CYP2C70; PLA2G6; ACCN3; MAPK11; PIK3CD; ACCN4; GNAQ; PLA2G4F; PLCB1
    Regulation of actin cytoskeleton FGD3; ACTG1; ITGA5; SRC; ARHGEF1; PIK3R3A; VCLA; FGF19; MYL2B; PFN2
    Insulin signaling pathway PHKB; RHEB; CALML5; FOXO1B; SOCS1A; PPP1CAB; G6PCA.2; PIK3R1; SOCS4; MAP2K2A
    Progesterone-mediated oocyte maturation MAD2L1; PDE3B; MAPK12; Adcy4; MAPK1; RPS6KA6; RPS6KA1; HSP90AA1; CDC16; CDK1
    Estrogen signaling pathway RAF1; ESR2; FKBP5; GNAS; PRKCD; MAPK3; ITPR3; HSP90AB1; HSPA1A; GNAI3
    Prolactin signaling pathway SOCS2; FOXO3; MAPK3; SHC3; SLC2A2; IRF1; INS; STAT5A; PIK3R3; MAPK12
    Thyroid hormone signaling pathway BMP4; PDPK1; PRKACA; GSK3B; FXYD2; PLCD1; HDAC1; NOTCH2; SLC16A10; KRAS
    Oxytocin signaling pathway PPP3CB; NFATC2; PLCB2; CAMKK1; MAPK1; GNAI1; CALM2; RGS2; PTGS2; CALML3
    Regulation of lipolysis in adipocytes PRKACG; NPY; PIK3CB; AQP7; ABHD5; PRKACB; TSHB; Adcy4; GNAI2; PIK3R2
    Type II diabetes mellitus PIK3R3; MTOR; MAPK10; HK3; PRKCZ; INS2; INSR; SOCS2; PIK3CG; MAPK9
    Insulin resistance PRKAG2A; SLC27A2; PIK3CB; PYGMA; SLC2A1; MAPK10; PCK2; PIK3CG; PCK1; AKT2L
    Non-alcoholic fatty liver disease (NAFLD) NDUFS2; PIK3R2; KCNA3; ADIPOR2; EIF2AK3; AKT1; PRKAA1; PPARA; NDUFA4L2; MAPK10
    Aldosterone-regulated sodium reabsorption MAPK1; PDPK1; MAPK3; HSD11B2; ATP1B1; PRKCB; ALPHA-ENAC; INS; INS1; PRKCG
    Carbohydrate digestion and absorption AMY1A; PIK3CB; AKT1; AMY2A5; G6PC3; SI; AMY2A2; G6PC; PIK3CA; SLC2A5
    Bacterial invasion of epithelial cells ELMO1; SEPT3; ARPC1B; CAV3; CAV1; ITGB1; CLTC; BCAR1; SEPT1; PXN
    Chagas disease (American trypanosomiasis) PLCB2; TGFB2; PLCB1; GNAI2; NFKB1; PIK3R1; SMAD3; IL1B2; PIK3CA; PPP2R1A
    Toxoplasmosis NOS2; IKBKG; ALOX5; Toxoplasma Gondii Microneme Protein MIC3; HSPA1L; LY96; HLA-DMB; MAPK10; GNAI2; CD40
    Amoebiasis PIK3CB; COL1A2; C9; PIK3R1; LAMA2; COL5A2; HSPB1; PIK3R5; PRKACA; COL4A3
    Hepatitis C RELA; TRAF2; NFKBIA; IFNA17; IFNB1; SCARB1; PPP2R2B; CLDN23; PIK3R3; PIK3R2
    Hepatitis B MAP3K1; DDX3X; EGR3; MAPK10; NFKBIA; DDB2; NFATC1; MAPK3; HSPG2; PRKCB
    Measles IFNA14; IFNA13; HSPA1A; AKT2; TLR4; IL2RB; IFNA10; TLR9; TNFRSF10B; IFNA12
    Influenza A IFNA12; RSAD2; PRKCB; PIK3R5; HLA-DOA; MAPK1; IFNAR1; Ccl12; LOC780933; BLA
    HTLV-I infection TERT; FZD6; GPS2; DVL3; ANAPC1; PIK3R1; HRAS; SLC25A5; ITGB2; SLC25A6
    Epstein-Barr virus infection HLA-C; CD44; GSK3B; POLR3B; TRADD; POLR3E; NUP214; TRAF5; POLR2K; PSMC3
    Pathways in cancer TRP53; HSP90AB1; PML; RBX1; MDM2; EP300; APC; BIRC3; FZD1; RASGRP3
    Viral carcinogenesis IKBKG; RANBP1; PSMC1; HIST2H2BE; HIST1H4A; GTF2B; ACTN2; STAT3; HIST1H4M; HDAC10
    Proteoglycans in cancer IGF1; PIK3CG; WNT8A; TFAP4; MAPK11; PRKCA; MAPK12; CAMK2D; PLCG1; CAMK2A
    Colorectal cancer GSK3B; AXIN2; MLH1; RAC1; RAC2; MAPK10; PIK3CA; APC; CASP9; MAPK8
    Renal cell carcinoma RAP1A; AKT1; EP300; PIK3R1; BRAF; PIK3R5; TGFB2; ARNT; MET; RAF1
    Pancreatic cancer PIK3CB; BAD; STAT1; RB1; AKT2; NFKB1; RAC3; MAPK9; ERBB2; SMAD3
    Endometrial cancer HRAS; ERBB2; PIK3R1; LEF1; MAP2K2; CDH1; AXIN1; MAPK1; PDPK1; RAF1
    Glioma CALM3; PRKCB; TRP53; CAMK2G; CALM4; MAPK3; PIK3R2; PIK3R3; CAMK2D; IGF1R
    Prostate cancer MDM2; TRP53; HRAS; GSTP1; MAP4K1; GRB2; MTOR; TCF7; IKBKB; SRD5A2
    Melanoma FGF7; FGF13; FGFR1; NRAS; FGF19; FGF5; FGF10; HGF; PIK3R2; BRAF
    Chronic myeloid leukemia CTBP1; MECOM; MAP2K1; BRAF; PIK3CA; CCND1; IKBKG; PTPN11; BAD; CDK6
    Acute myeloid leukemia RARA; PIK3R2; AKT2; PML; PIK3R5; RPS6KB2; NFKB1; STAT5B; PIK3CD; MYC
    Small cell lung cancer PIK3CG; TRAF5; IKBKG; LAMC2; BIRC8; MAX; TRAF4; LAMA2; FHIT; SKP2
    Non-small cell lung cancer PLCG2; RXRB; NRAS; PLCG1; RAF1; PIK3CG; PRKCB; RB1; RASSF1; FOXO3
    Central carbon metabolism in cancer HK2; FGFR2; AKT1; MAP2K2; TP53; HK3; MET; MAP2K1; SLC7A5; PDHA1
    Choline metabolism in cancer MAP2K1; PDGFB; MAPK1; PIK3R3; DGKQ; TSC1; SLC22A1; PIK3CD; MAPK10; PIK3R5

    PIK3CD has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by PIK3CD itself. We selected most functions PIK3CD had, and list some proteins which have the same functions with PIK3CD. You can find most of the proteins on our site.

    Function Related Protein
    1-phosphatidylinositol-3-kinase activity PIK3CG; PIK3CB; PIK3CA; PIK3R3; PIK3C2G; PIK3CD; PIK3C2B; ATM; PIK3C2A; PIK3C3
    1-phosphatidylinositol-4-phosphate 3-kinase activity PIK3C2A; PIK3CD; PIK3CA; PIK3C2G; PIK3CB; PIK3CG; PIK3C2B
    ATP binding INSR; NAT1; ORC1L; TRP53; SKIV2L; AK3; CHST13; RBM4.3; LIG3; TSSK1
    phosphatidylinositol 3-kinase activity PIK3CA; PIK3CD; PIK3CB; PIK3CG; PIK3C2A
    phosphatidylinositol-4,5-bisphosphate 3-kinase activity PIK3CA; PIK3CG; PIK3CB; PIK3CD
    protein binding NOC2L; MCM4; PEX14; C7orf31; DUSP26; RUFY4; PSMD10; CMTM2A; BAK1; C10orf137

    PIK3CD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIK3CD here. Most of them are supplied by our site. Hope this information will be useful for your research of PIK3CD.

    PIK3R1; 1-phosphatidyl-1d-myo-inositol; pi3kr1_cerae_protein; HRAS; CD37; NCK1; TNPO2; FAM195A; ASCC2; RALY

    Related Services & Products

    Apply For A Coupon

    $50 OFF Your First Purchase

    Apply For a Coupon

    Enter your email here to subscribe.

    creative biomart inc.

    Easy access to products and services you need from our library via powerful searching tools.

    Follow Us

    Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved.