Recombinant Human PIK3CD protein, His & T7-tagged

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Recombinant Human PIK3CD protein, His & T7-tagged

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Cat.No. : PIK3CD-1727H
Product Overview : Recombinant Human PIK3CD aa. (Val774~Gln1044 (Accession # O00329)) fused with N-terminal His & T7 tag was produced in E. coli cells.
Description : Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.
Source : E. coli
Species : Human
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 34.8kDa
Protein length : Val774~Gln1044 (Accession # O00329)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Isoelectric Point : 8.7
SDS-PAGE :

Gene Name : PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [ Homo sapiens (human) ]
Official Symbol : PIK3CD
Synonyms : PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; APDS; PI3K; IMD14; p110D; P110DELTA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; PI3-kinase p110 subunit delta; PI3Kdelta; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; phosphoinositide-3-kinase C; phosphoinositide-3-kinase, catalytic, delta polypeptide variant p37delta; ptdIns-3-kinase subunit p110-delta
Gene ID : 5293
mRNA Refseq : NM_005026.4
Protein Refseq : NP_005017.3
UniProt ID : O00329
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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