pitpna
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  • Official Full Name
  • phosphatidylinositol transfer protein, alpha
  • Background
  • This gene encodes a member of a family of lipid-binding proteins that transfer molecules of phosphatidylinositol or phosphatidylcholine between membrane surfaces. The protein is implicated in phospholipase C signaling and in the production of phosphatidylinositol 3,4,5-trisphosphate (PIP3) by phosphoinositide-3-kinase.
  • Synonyms
  • PITPNA; phosphatidylinositol transfer protein, alpha; phosphotidylinositol transfer protein , PITPN; phosphatidylinositol transfer protein alpha isoform; VIB1A; MGC99649; Phosphatidylinositol transfer protein alpha; Phosphotidylinositol transfer protein; PITP alpha; PITPNB; PtdIns transfer protein alpha; PtdInsTP; PI-TP-alpha; ptdInsTP alpha; PITPN; PI-TPalpha
Cat.#:PITPNA-3381HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PITPNA, His-tagged
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Cat.#:PITPNA-669HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PITPNA Protein, His-tagged
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Cat.#:PLA2G1B-898HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLA2G1B, His-tagged
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Cat.#:PITPNA-12843MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PITPNA Protein
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Cat.#:PITPNA-4473RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PITPNA Protein
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Cat.#:PITPNA-3441RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PITPNA Protein, His-tagged
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Cat.#:PITPNA-3167HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PITPNA 293 Cell Lysate
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Involved Pathway

PITPNA involved in several pathways and played different roles in them. We selected most pathways PITPNA participated on our site, such as Axon guidance, Developmental Biology, EGFR1 Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PITPNA were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Axon guidance
NTNG1; CFL2; EFNA4; CXCR4; NFATC4; SEMA3C; DUSP6; RAC3; EPHA10; TRIO
Developmental Biology
FGFR1B; AP2S1; KCNQ2; MED8; MYL12A; MED16; RGMA; MEF2B; FRS2B; ARHGEF28
EGFR1 Signaling Pathway
KRT8; TNIP1; KLF11; ZNF259; ARF4; SPRY2; AP2A1; PITPNA; MTA2; RGS16
Netrin-1 signaling
TRPC4; RGMA; RGMB; SIAH2; HFE2; EZRA; NTN1B; RNF8; TRPC5; NTN1A
Role of second messengers in netrin-1 signaling
TRPC5; PITPNA; TRPC4

Protein Function

PITPNA has several biochemical functions, for example, lipid binding, phosphatidylcholine transporter activity, phosphatidylinositol transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PITPNA itself. We selected most functions PITPNA had, and list some proteins which have the same functions with PITPNA. You can find most of the proteins on our site.
Function
Related Protein
Function lipid binding
Related Protein BPIFB1; INPP4B; UNC119.1; APOE; UNC119B; EPN3; BPIFB6; OSBPL6; FAM123A; YBX2
Function phosphatidylcholine transporter activity
Related Protein PITPNBL; ABCB4; PCTP; PITPNA
Function phosphatidylinositol transporter activity
Related Protein PITPNA; PITPNC1; PITPNBL; PITPNM1; PITPNM3; SCP2; TNFAIP8L3

Interacting Protein

PITPNA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PITPNA here. Most of them are supplied by our site. Hope this information will be useful for your research of PITPNA.
GTF2F2; MORF4L2; PMVK; HSDL1; MLKL; SIRT3; CSNK2B; pi3p; PLK1; Dync1li1; Cdc26

PITPNA Related Articles

Dovas, A; Choi, Y; et al. Serine 34 Phosphorylation of Rho Guanine Dissociation Inhibitor (RhoGDI alpha) Links Signaling from Conventional Protein Kinase C to RhoGTPase in Cell Adhesion. JOURNAL OF BIOLOGICAL CHEMISTRY 285:23294-23306(2010).
Speak, AO; Cerundolo, V; et al. CD1d presentation of glycolipids. IMMUNOLOGY AND CELL BIOLOGY 86:588-597(2008).